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Your Position: Home > Protein > HLA-A*0201 & B2M & EBV LMP2 (FLYALALLL) > HL2-HP2H3

PE-Labeled Human HLA-A*02:01&B2M&EBV LMP2 (FLYALALLL) Tetramer Protein

Streptavidin Protein - PE (STN-NP117, STN-NP119), supporting the assembly of your own MHC Tetramers!

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  • Source
    PE-Labeled Human HLA-A*02:01&B2M&EBV LMP2 (FLYALALLL) Tetramer Protein(HL2-HP2H3) is expressed from human 293 cells (HEK293). It contains AA Gly 25 - Ile 308 (HLA-A*02:01) & Ile 21 - Met 119 (B2M) & FLYALALLL peptide (Accession # AAA59606.1 (HLA-A*02:01) & P61769-1 (B2M) & FLYALALLL).
    Predicted N-terminus: Gly 25 & Ile 21
  • Molecular Characterization

    PE-Labeled Human HLA-A*02:01&B2M&EBV LMP2 (FLYALALLL) Tetramer Protein is assembled by biotinylated monomer (HL2-H82Er) and PE-labeled streptavidin.

    Biotinylated Human HLA-A*02:01&B2M&EBV LMP2 (FLYALALLL) Complex Protein is produced by co-expression of HLA and B2M loaded with EBV LMP2 peptide. Biotinylated Human HLA-A*02:01&B2M&EBV LMP2 (FLYALALLL) Complex Protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag™).

  • Conjugate

    PE

    Excitation Wavelength: 488 nm / 561 nm

    Emission Wavelength: 575 nm

  • Endotoxin
    Less than 1.0 EU per μg by the LAL method.
  • Formulation

    Lyophilized from 0.22 μm filtered solution in PBS, 1% BSA, pH7.4 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please protect from light and avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
  • Background
    Epstein-Bar Virus (EBV), also known as human herpesvirus 4, belongs to gamma herpes virus family and is a very common human virus worldwide. EBV causes infectious mononucleosis (IM) and also associates to some specific types of cancers such as Burkitt’s lymphoma (BL) and gastric carcinoma (GC). Glycoprotein B (gB) plays an important role in viral entry by binding with αvβ6/αvβ8 integrins to trigger the membrane fusion and entry process of epithelial cells, which makes it become an great target for EBV research. Epstein-Bar Virus (EBV), also known as human herpesvirus 4, belongs to gamma herpes virus family and is a very common human virus worldwide. EBV causes infectious mononucleosis (IM) and also associates to some specific types of cancers such as Burkitt’s lymphoma (BL) and gastric carcinoma (GC). Glycoprotein B (gB) plays an important role in viral entry by binding with αvβ6/αvβ8 integrins to trigger the membrane fusion and entry process of epithelial cells, which makes it become an great target for EBV research. The Human HLA-A*0201 EBV LMP2 (FLYALALLL) complex protein is a complex of HLA-A*0201 of the MHC Class I, B2M and FLYALALLL peptide of the EBV LMP2.
  • Clinical and Translational Updates

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Price(USD) : $2280.00

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