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Your Position: Home > IL-2 R beta & IL-2 R gamma

IL-2 R beta & IL-2 R gamma

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Part of Bioactivity data

ILG-H5254-SPR
Human_FcRn_Heterodimer_Protein_SPR

Human IL-2RB&IL-2RG Heterodimer Protein, Fc Tag&Fc Tag (Cat. No. ILG-H5254) captured on CM5 chip via anti-human IgG Fc antibody can bind IL-2, Tag Free (Cat. No. IL2-H4113) with an affinity constant of 0.123 nM as determined in a SPR assay (Biacore T200) (Routinely tested).

ILG-C82F4-BLI
Human_FcRn_Heterodimer_Protein_Bli

Loaded Biotinylated Cynomolgus IL-2RB&IL-2RG, Fc,Avitag&Fc,Avitag (Cat. No. ILG-C82F4) on SA Biosensor, can bind Human IL-2, Tag Free (Cat. No. IL2-H4113) with an affinity constant of 2.34 nM as determined in BLI assay (ForteBio Octet Red96e) (Routinely tested).

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IL-2 R beta & IL-2 R gamma Molecule Synonym Name

IL-2 R beta & IL-2 R gamma,IL-2RB & IL-2RG

IL-2 R beta & IL-2 R gamma Molecule Background

Both Interleukin-2 receptor subunit beta and Interleukin-2 receptor subunit gamma are receptor for interleukin-2. Common subunit for the receptors for a variety of interleukins. Interacts with SHB upon interleukin stimulation. Probably in association with IL15RA, involved in the stimulation of neutrophil phagocytosis by IL15. This beta subunit is involved in receptor mediated endocytosis and transduces the mitogenic signals of IL2. IL2R exists in 3 different forms: a high affinity dimer, an intermediate affinity monomer (beta subunit), and a low affinity monomer (alpha subunit). The high and intermediate affinity forms also associate with a gamma subunit.

IL-2 R beta & IL-2 R gamma References

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