IgG1 Fc Protein - ACROBiosystems

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IgG1 Fc


IG1-M8211	Mouse	Biotinylated Mouse IgG1 Fc protein, Avitag™
IG1-H82Eb	Human	Biotinylated Human IgG1 Fc Protein, Avitag™,His Tag (MALS-verified)
IG1-H52C9	Human	Human IgG1 Fc Protein, Flag Tag
IG1-H52G6	Human	Human IgG1 Fc Protein, gD Tag
IG1-H8213	Human	Biotinylated Human IgG1 Fc protein, Avitag™
IG1-H82E2	Human	Biotinylated Human IgG1 Fc Protein, Avitag™,His Tag
IG1-H5225	Human	Human IgG1 Fc Protein, His Tag
IG1-M5208	Mouse	Mouse IgG1 Fc Protein, Tag Free
FCC-H5214	Human	Human IgG1 Fc Protein, Tag Free (MALS verified)

Cat. No.

Species

Product Description

Structure

Purity

Feature

IG1-M8211

Mouse

Biotinylated Mouse IgG1 Fc protein, Avitag™

IG1-H82Eb

Human

Biotinylated Human IgG1 Fc Protein, Avitag™,His Tag (MALS-verified)

IG1-H52C9

Human

Human IgG1 Fc Protein, Flag Tag

IG1-H52G6

Human

Human IgG1 Fc Protein, gD Tag

IG1-H8213

Human

Biotinylated Human IgG1 Fc protein, Avitag™

IG1-H82E2

Human

Biotinylated Human IgG1 Fc Protein, Avitag™,His Tag

IG1-H5225

Human

Human IgG1 Fc Protein, His Tag

IG1-M5208

Mouse

Mouse IgG1 Fc Protein, Tag Free

FCC-H5214

Human

Human IgG1 Fc Protein, Tag Free (MALS verified)

Part of Bioactivity data

IG1-H8213-SPR

Human FCGRT&B2M Heterodimer Protein, His Tag (SPR & BLI verified) (Cat. No. FCN-H52W7) captured on CM5 Chip via anti-His antibody can bind Biotinylated Human IgG1 Fc, Avitag (Cat. No. IG1-H8213) with an affinity constant of 0.377 μM as determined in SPR assay (Biacore 8K) (Routinely tested).

Protocol

FCC-H5214-SPR

Human FCGRT&B2M Heterodimer Protein, His Tag (Cat. No. FCN-H52W7) captured on CM5 Chip via anti-His antibody can bind Human IgG1 Fc, Tag Free (Cat. No. FCC-H5214) with an affinity constant of 0.957 μM as determined in SPR assay (Biacore 8K) (Routinely tested).

Protocol

Synonym Name

IgG1

Background

Crystallizable fragments composed of the carboxy-terminal halves of both IMMUNOGLOBULIN HEAVY CHAINS linked to each other by disulfide bonds. Fc fragments contain the carboxy-terminal parts of the heavy chain constant regions that are responsible for the effector functions of an immunoglobulin (COMPLEMENT fixation, binding to the cell membrane via FC RECEPTORS, and placental transport). IgG1 Fc was reported has a novel role as a potential anti-inflammatory drug for treatment of human autoimmune diseases.

Clinical and Translational Updates