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Your Position: Home > IgG1 Fc

IgG1 Fc

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Cat. No. Species Product Description Structure Purity Feature
IG1-H8212 Human Biotinylated Human IgG1 Fc (C103S, D239E, L241E) Protein, Avitag™
IG1-H8212-structure
IG1-H52H1 Human Human IgG1 Fc (C103S, D239E, L241E) Protein, Tag Free (MALS verified)
IG1-H52H1-structure
IG1-H52H1-sds
IG1-H52H8 Human Human IgG1 Fc (C103S, M135Y, S137T, T139E, H316K, N317F) Protein, His Tag
IG1-H52H8-structure
IG1-H52H8-sds
IG1-H52H9 Human Human IgG1 Fc (C103S, L117F, L118E, P214S) Protein, His Tag
IG1-H52H9-structure
IG1-H52H9-sds
IG1-H82E9 Human Biotinylated Human IgG1 Fc (C103S) Protein, Avitag™,His Tag
IG1-H82E9-structure
IG1-M8211 Mouse Biotinylated Mouse IgG1 Fc protein, Avitag™ (MALS verified)
IG1-M8211-structure
IG1-M8211-sds
IG1-H52C9 Human Human IgG1 Fc (C103S) Protein, Flag Tag (MALS verified)
IG1-H52C9-structure
IG1-H52C9-sds
IG1-H52G6 Human Human IgG1 Fc (C103S) Protein, gD Tag (MALS verified)
IG1-H52G6-structure
IG1-H52G6-sds
IG1-H8213 Human Biotinylated Human IgG1 Fc protein, Avitag™ (MALS verified)
IG1-H8213-structure
IG1-H8213-sds
IG1-H5225 Human Human IgG1 Fc Protein, His Tag (MALS verified)
IG1-H5225-structure
IG1-H5225-sds
IG1-M5208 Mouse Mouse IgG1 Fc Protein, Tag Free (MALS verified)
IG1-M5208-structure
IG1-M5208-sds
FCC-H5214 Human Human IgG1 Fc Protein, Tag Free (MALS verified)
FCC-H5214-structure
FCC-H5214-sds

Part of Bioactivity data

IG1-H52H8-SPR
IgG1 Fc SPR

Human IgG1 Fc (C103S, M135Y, S137T, T139E, H316K, N317F), His Tag (Cat. No. IG1-H52H8) immobilized on CM4 Chip can bind Human FCGRT&B2M Heterodimer Protein, His Tag (Cat. No. FCN-H52W7) with an affinity constant of 8.45 nM as determined in a SPR assay (Biacore 8K) (Routinely tested).

Protocol
IG1-H52H9-SPR
Human_FcRn_Heterodimer_Protein_SPR

Human IgG1 Fc (C103S, L117F, L118E, P214S), His Tag (Cat. No. IG1-H52H9) immobilized on CM4 Chip can bind Human FCGRT&B2M Heterodimer Protein, His Tag (Cat. No. FCN-H52W7) with an affinity constant of 1.42 μM as determined in a SPR assay (Biacore 8K) (Routinely tested).

Protocol

Customer Reviews

Synonym Name

IgG1

Background

Crystallizable fragments composed of the carboxy-terminal halves of both IMMUNOGLOBULIN HEAVY CHAINS linked to each other by disulfide bonds. Fc fragments contain the carboxy-terminal parts of the heavy chain constant regions that are responsible for the effector functions of an immunoglobulin (COMPLEMENT fixation, binding to the cell membrane via FC RECEPTORS, and placental transport). IgG1 Fc was reported has a novel role as a potential anti-inflammatory drug for treatment of human autoimmune diseases.

Clinical and Translational Updates

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