| Cat. No. | Species | Product Description | Structure | Purity | Feature |
|---|---|---|---|---|---|
| MBS-K040 | Human | Human B7-H3(4Ig)-coupled Magnetic Beads |
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| B73-C52Ha | Cynomolgus | Cynomolgus B7-H3 / CD276 Protein, His Tag (MALS verified) |  |
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| B73-H82F5 | Human | Biotinylated Human B7-H3 / CD276 Protein, Fc,Avitag™ (MALS verified) |  |
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| B73-H82E6 | Human | Biotinylated Human B7-H3 / CD276 Protein, Avitag™,His Tag |  |
|
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| B73-M52H4 | Mouse | Mouse B7-H3 / CD276 Protein, His Tag (MALS verified) |  |
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| B73-M5255 | Mouse | Mouse B7-H3 / CD276 Protein, Fc Tag (MALS verified) |  |
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| B73-H52E2 | Human | Human B7-H3 / CD276 Protein, His Tag (MALS verified) |  |
|
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| B73-H5253 | Human | Human B7-H3 / CD276 Protein, Fc Tag (MALS verified) |  |
|
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Immobilized Cynomolgus B7-H3, His Tag (Cat. No. B73-C52Ha) at 2 μg/mL (100 μL/well) can bind Monoclonal Anti-Human B7-H3 / B7-H3 (4Ig) Antibody, Human IgG1 with a linear range of 0.1-4 ng/mL (QC tested).
The purity of Cynomolgus B7-H3, His Tag (Cat. No. B73-C52Ha) was more than 90% and the molecular weight of this protein is around 65-85 kDa verified by SEC-MALS.
Immobilized Cynomolgus B7-H3, His Tag (Cat. No. B73-C52Ha) at 2 μg/mL (100 μL/well) can bind Monoclonal Anti-Human B7-H3 / B7-H3 (4Ig) Antibody, Human IgG1 with a linear range of 0.1-4 ng/mL (QC tested).
| Name | Research Code | Research Phase | Company | Indications | Clinical Trials |
|---|---|---|---|---|---|
| MGC-018 | MGC-018 | Phase 2 Clinical | Macrogenics | Neoplasms | Details |
| SCRI-CARB7H3 | SCRI-CARB7H3 | Phase 1 Clinical | Seattle Children'S Hospital | Central Nervous System Neoplasms; Glioma | Details |
| Monoclonal antibody 8H9 I-124 | 124I-8H9; 124I-8H9-(B7-H3) | Phase 2 Clinical | Memorial Sloan Kettering Cancer Center | Glioma | Details |
| DS-7300 | DS-7300 | Phase 2 Clinical | Daiichi Sankyo Co Ltd | Neoplasms | Details |
| 4SCAR-276 | 4SCAR-276 | Phase 2 Clinical | Shenzhen Geno-Immune Medical Institute | Neoplasms | Details |
| Monoclonal antibody 8H9 I-131 | 8H9-MAb; 131-I-8H9; 131I-8H9-(B7-H3) | Phase 3 Clinical | Memorial Sloan Kettering Cancer Center | Neuroblastoma; Peritoneal Neoplasms; Neoplasm Metastasis | Details |
| B7-H3 CAR-T cell therapy (Zhejiang University) | Phase 2 Clinical | Zhejiang University Alumni Association (Singapore) | Glioblastoma | Details | |
| Enoblituzumab | MGA-271 | Phase 2 Clinical | Macrogenics | Head and Neck Neoplasms; Rhabdomyosarcoma; Squamous Cell Carcinoma of Head and Neck; Desmoplastic Small Round Cell Tumor; Carcinoma, Renal Cell; Wilms Tumor; Triple Negative Breast Neoplasms; Urinary Bladder Neoplasms; Osteosarcoma; Neuroblastoma; Prostatic Neoplasms; Sarcoma, Ewing; Melanoma; Carcinoma, Non-Small-Cell Lung | Details |
| Anti-CD276 CAR T-cell therapy (The First Affiliated Hospital of Zhengzhou University) | Phase 1 Clinical | Stomach Neoplasms; Osteosarcoma; Neuroblastoma; Lung Neoplasms | Details | ||
| Mirzotamab clezutoclax | ABBV-155 | Phase 1 Clinical | Abbvie Inc | Hematologic Neoplasms; Solid tumours | Details |
| 177Lu-DTPA-omburtamab | Phase 2 Clinical | Y-Mabs | Solid tumours; Meningeal Neoplasms | Details | |
| Omburtamab I-131 | Phase 1 Clinical | Y-Mabs | Central Nervous System Neoplasms; Sarcoma; Neuroblastoma; Brain Neoplasms | Details | |
| Orlotamab | MGD-009; B7-H3 x CD3 | Phase 2 Clinical | Macrogenics | Mesothelioma; Melanoma; Carcinoma, Non-Small-Cell Lung; Thyroid Neoplasms; Neurofibrosarcoma; Neuroblastoma; Sarcoma; Prostatic Neoplasms; Breast Neoplasms; Ovarian Neoplasms; Sarcoma, Synovial; Urinary Bladder Neoplasms; Wilms Tumor; Pancreatic Neoplasms; Colonic Neoplasms; Squamous Cell Carcinoma of Head and Neck; Carcinoma, Renal Cell; Rhabdomyosarcoma | Details |
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