Biotinylated Human IL-23A&IL-12B Heterodimer Protein, His,Avitag&Tag Free (Cat. No. ILB-H82W6) stimulates secretion of IL-17 by mousespleen cells. The ED50 for this effect is 0.191-0.2173 ng/mL (Routinely tested).
Cell based assay shows that the secretion of IL-17 induced by Biotinylated Human IL-23A&IL-12B Heterodimer Protein, His,Avitag&Tag Free (Cat. No. ILB-H82W6) is inhibited by increasing concentration of the anti-human IL-23 neutralizing antibody. The IC50 is between 0.25-1.40 ng/mL (Routinely tested).
Captured Biotinylated Human IL-23A&IL-12B Heterodimer Protein, His,Avitag&Tag Free (Cat. No. ILB-H82W6) on Biotin CAP - Series S sensor Chip can bind Human IL-23 R, His Tag (Cat. No. ILR-H52H4) affinity constant of 4.77 nM as determined in a SPR assay (Biacore T200) (Routinely tested).
Captured Human IL-23 R, Fc Tag (Cat. No. ILR-H5254) on CM5 chip via anti-human IgG Fc antibodies surface can bind Human IL-23A&IL-12B Heterodimer Protein, His Tag&Tag Free (Cat. No. ILB-H52W5) with an affinity constant of 5.36 nM as determined in a SPR assay (Biacore T200) (Routinely tested).
| Cat. No. | Species | Product Description | Structure | Purity | Feature |
|---|---|---|---|---|---|
| ILB-CM52W8 | Cynomolgus & Mouse | Cynomolgus IL-23 alpha & Mouse IL-12 beta Heterodimer Protein, His Tag&Tag Free |  |
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| ILB-H82W6 | Human | Biotinylated Human IL-23 alpha&IL-12 beta Heterodimer Protein, His,Avitag™&Tag Free |  |
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| ILB-M52W7 | Mouse | Mouse IL-23 alpha&IL-12 beta Heterodimer Protein, His Tag&Tag Free |  |
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| ILB-HM52W6 | Human & Mouse | Human IL-23 alpha & Mouse IL-12 beta Heterodimer Protein, His Tag&Tag Free |  |
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| ILB-H52W5 | Human | Human IL-23 alpha&IL-12 beta Heterodimer Protein, His Tag&Tag Free |  |
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