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Nectin-2

Nectin-2 Product List

Cat. No. Species Product Description Structure Purity Feature
PV2-H52E2 Human Human Nectin-2 / CD112 Protein
PV2-H52E2-structure
PV2-H52E2-sds
PV2-H52E2-elisa_1
CD2-H82F8 Human Biotinylated Human Nectin-2 / CD112 / PVRL2 Protein, Fc Tag, Avi Tag
CD2-H82F8-structure
CD2-H82F8-sds
CD2-H82F8-elisa_1
PV2-H5253 Human Human Nectin-2 / CD112 Protein, Fc Tag
PV2-H5253-structure
PV2-H5253-sds
PV2-H5253-elisa_1

Nectin-2 Molecule Synonym Name

CD112,Nectin-2,PVRL2

Nectin-2 Molecule Background

Poliovirus receptor-related 2 (PVRL2) is also known as nectin-2 and CD112 (formerly herpesvirus entry mediator B, HVEB), which is a human plasma membrane glycoprotein. PVRL2 is one of the plasma membrane components of adherens junctions. PVRL2 also serves as an entry for certain mutant strains of herpes simplex virus and pseudorabies virus, and it is involved in cell to cell spreading of these viruses. Variations in PVRL2 gene have been associated with differences in the severity of multiple sclerosis. Also, PVRL2 binds with low affinity to TIGIT. Furthermore, PVRL2 acts as a receptor for herpes simplex virus 1 (HHV-1) mutant Rid1, herpes simplex virus 1 (HHV-2) and pseudorabies virus (PRV).

Nectin-2 References

Nectin-2 Related Molecule

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