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Your Position: Home > Transferrin R

Transferrin R

Brief Information

Name:Transferrin receptor protein 1
Target Synonym:TFRC,T9,sTfR,Transferrin receptor protein 1,TR,Transferrin Receptor,P90,Transferrin Receptor (P90, CD71),CD71 Antigen,IMD46,CD71,TfR1,Trfr,TfR
Number of Launched Drugs:0
Number of Drugs in Clinical Trials:2
Lastest Research Phase:Approved

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Part of Bioactivity data

TFR-M8249-ELISA
 Transferrin R ELISA

Immobilized Biotinylated Mouse Transferrin R, His Tag, primary amine labeling (Cat. No. TFR-M8249) at 1 μg/mL (100 μL/well) on streptavidin (Cat. No. STN-N5116) precoated (0.5 μg/well) plate can bind Mouse Transferrin, Mouse IgG2a Fc Tag, low endotoxin (Cat. No. TRN-M525b) with a linear range of 0.2-16 ng/mL (QC tested).

TFR-M8249-MALS-HPLC
Transferrin R MALS images

The purity of Biotinylated Mouse Transferrin R, His Tag, primary amine labeling (Cat. No. TFR-M8249) is more than 95% and the molecular weight of this protein is around 140-170 kDa verified by SEC-MALS.

Customer Reviews

Synonym Name

CD71,TFRC,TFR,sTfR,TfR1,Trfr,T9,p90

Background

CD antigen CD71 is also known as Transferrin receptor protein 1, TfR, sTfR, p90, TfR1, Trfr, which belongs to the peptidase M28 family and M28B subfamily. CD71 /TFR contains one PA (protease associated) domain. CD71 / TfR1 is required for iron delivery from transferrin to cells. CD71 is a potential new target in cases of human leukomia & lymphoma. CD71 /TFRC / TfR has been shown to interact with GABARAP and HFE.

Clinical and Translational Updates

Public Drug Information

Name Research Code Research Phase Company First Brand Name First Approved Country First Indication First Approved Company First Approved Date Indications Clinical Trials
Pabinafusp alfa JR-141 Approved Jcr Pharmaceuticals Co Ltd Japan Mucopolysaccharidosis II Jcr Pharmaceuticals Co Ltd 2021-03-23 Mucopolysaccharidosis II Details

Clinical Drug Information

Name Research Code Research Phase Company Indications Clinical Trials
Trontinemab RO-7126209; RG-6102 F. Hoffmann-La Roche Ltd Details
Lepunafusp alfa JR-171 Phase 2 Clinical Jcr Pharmaceuticals Co Ltd Mucopolysaccharidosis I Details
PPMX-T003 PPMX-T003 Phase 1 Clinical Perseus Proteomics Inc Polycythemia Vera Details
AOC-1001 Phase 2 Clinical Avidity Biosciences Inc Myotonic Disorders; Genetic Diseases, Inborn; Myotonic Dystrophy; Musculoskeletal Diseases; Muscular Disorders, Atrophic; Muscular Atrophy; Heredodegenerative Disorders, Nervous System; Neuromuscular Diseases; Muscular Diseases; Nervous System Diseases; Muscular Dystrophies; Neurodegenerative Diseases Details
Human apotransferrin (Sanquin Blood Supply Foundation) Phase 3 Clinical Sanquin Plasma Products Bv Iron Metabolism Disorders; beta-Thalassemia Details
DYNE-251 DYNE251 Phase 2 Clinical Dyne Therapeutics Inc Muscular Dystrophy, Duchenne Details
CX-2029 ABBV-2029; ABBV-CX-2029; CX-2029 Phase 2 Clinical Abbvie Inc, Cytomx Therapeutics Inc Head and Neck Neoplasms; Solid tumours; Esophageal Neoplasms; Lymphoma, Large B-Cell, Diffuse; Carcinoma, Non-Small-Cell Lung Details

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