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Transferrin R

Transferrin R Molecule Information

Name:Transferrin receptor protein 1
Target Synonym:TfR1;TfR;p90;TR;CD_antigen: CD71;Trfr;T9;TFRC;CD71
Number of Launched Drugs:0
Number of Drugs in Clinical Trials:3
Lastest Research Phase:Phase ?

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Transferrin R Part of Bioactivity data

TFR-C524a-ELISA
Cynomolgus Transferrin R, His TagCynomolgus Transferrin R, His Tag (Cat. No. TFR-C524a) ELISA bioactivity

Immobilized Human Transferrin, His Tag (Cat. No. TRN-H4229) at 5 μg/mL (100 μL/well) can bind Cynomolgus Transferrin R, His Tag (Cat. No. TFR-C524a) with a linear range of 0.2-6 ng/mL (QC tested).

TFR-H82E5-MALS-HPLC
Biotinylated Human Transferrin R, His,Avitag (Cat. No. ) MALS images

The purity of Biotinylated Human Transferrin R, His,Avitag(Cat. No. TFR-H82E5) was more than 90% and the molecular weight of this protein is around 160-180 kDa verified by SEC-MALS.

Bioactivity-ELISA
Biotinylated Human Transferrin R, His,AvitagBiotinylated Human Transferrin R, His,Avitag (Cat. No. TFR-H82E5) ELISA bioactivity

Immobilized Five-Minute 6-plex Mouse mAb Isotyping Kit (Cat. No. E001-K001) at 2 μg/mL (100 μL/well) can bind Biotinylated Human Transferrin R, His,Avitag (Cat. No. TFR-H82E5) with a linear range of 2-63 ng/mL (QC tested).

Transferrin R Molecule Synonym Name

CD71,TFRC,TFR,sTfR,TfR1,Trfr,T9,p90

Transferrin R Molecule Background

CD antigen CD71 is also known as Transferrin receptor protein 1, TfR, sTfR, p90, TfR1, Trfr, which belongs to the peptidase M28 family and M28B subfamily. CD71 /TFR contains one PA (protease associated) domain. CD71 / TfR1 is required for iron delivery from transferrin to cells. CD71 is a potential new target in cases of human leukomia & lymphoma. CD71 /TFRC / TfR has been shown to interact with GABARAP and HFE.

Transferrin R References

Transferrin R Clinical Drug Information

Name Research Code Research Phase Company Indications Clinical Trials
SGT-94 SGT-94; SGT-RB94 Phase Ⅰ SynerGene Therapeutics Solid tumours Details
CX-2029 CX-2029 Phase Ⅱ CytomX Therapeutics, Abbvie Diffuse large B cell lymphoma, Solid tumours Details
Monoclonal antibody 42/6 Phase Ⅰ Nonindustrial source Cancer Details

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