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Your Position: Home > Transferrin R

Transferrin R

Brief Information

Name:Transferrin receptor protein 1
Target Synonym:TFRC,T9,sTfR,Transferrin receptor protein 1,TR,Transferrin Receptor,P90,Transferrin Receptor (P90, CD71),CD71 Antigen,IMD46,CD71,TfR1,Trfr,TfR
Number of Launched Drugs:0
Number of Drugs in Clinical Trials:2
Lastest Research Phase:Phase 2 Clinical

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Part of Bioactivity data

TFR-C8249-ELISA
Biotinylated Cynomolgus Transferrin R, His Tag, primary amine labelingBiotinylated Cynomolgus Transferrin R, His Tag, primary amine labeling (Cat. No. TFR-C8249) ELISA bioactivity

Immobilized Biotinylated Cynomolgus Transferrin R, His Tag, primary amine labeling (Cat. No. TFR-C8249) at 1 μg/mL (100 μL/well) on streptavidin (Cat. No. STN-N5116) precoated (0.5 μg/well) plate can bind Mouse Transferrin, Mouse IgG2a Fc Tag, low endotoxin (Cat. No. TRN-M525b) with a linear range of 0.3-10 ng/mL (QC tested).

TFR-M8249-MALS-HPLC
Biotinylated Mouse Transferrin R, His Tag, primary amine labeling (Cat. No. ) MALS images

The purity of Biotinylated Mouse Transferrin R, His Tag, primary amine labeling (Cat. No. TFR-M8249) is more than 95% and the molecular weight of this protein is around 145-177 kDa verified by SEC-MALS.

Bioactivity-ELISA
Biotinylated Mouse Transferrin R, His Tag, primary amine labelingBiotinylated Mouse Transferrin R, His Tag, primary amine labeling (Cat. No. TFR-M8249) ELISA bioactivity

Immobilized Biotinylated Mouse Transferrin R, His Tag, primary amine labeling (Cat. No. TFR-M8249) at 1 μg/mL (100 μL/well) on streptavidin (Cat. No. STN-N5116) precoated (0.5 μg/well) plate can bind Mouse Transferrin, Mouse IgG2a Fc Tag, low endotoxin (Cat. No. TRN-M525b) with a linear range of 0.2-16 ng/mL (QC tested).

Customer Reviews

Synonym Name

CD71,TFRC,TFR,sTfR,TfR1,Trfr,T9,p90

Background

CD antigen CD71 is also known as Transferrin receptor protein 1, TfR, sTfR, p90, TfR1, Trfr, which belongs to the peptidase M28 family and M28B subfamily. CD71 /TFR contains one PA (protease associated) domain. CD71 / TfR1 is required for iron delivery from transferrin to cells. CD71 is a potential new target in cases of human leukomia & lymphoma. CD71 /TFRC / TfR has been shown to interact with GABARAP and HFE.

Clinical and Translational Updates

Clinical Drug Information

Name Research Code Research Phase Company Indications Clinical Trials
AOC-1001 Phase 2 Clinical Avidity Biosciences Inc Myotonic Disorders; Myotonic Dystrophy; Muscular Atrophy Details
CX-2029 ABBV-CX-2029; CX-2029; ABBV-2029 Phase 2 Clinical Cytomx Therapeutics, Abbvie Inc Head and Neck Neoplasms; Solid tumours; Esophageal Neoplasms; Lymphoma, Large B-Cell, Diffuse; Carcinoma, Non-Small-Cell Lung Details
PPMX-T003(Perseus Proteomics) Phase 1 Clinical Polycythemia Vera Details

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