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Your Position: Home > Transferrin R

Transferrin R

Brief Information

Name:Transferrin receptor protein 1
Target Synonym:TFRC,T9,sTfR,Transferrin receptor protein 1,TR,Transferrin Receptor,P90,Transferrin Receptor (P90, CD71),CD71 Antigen,IMD46,CD71,TfR1,Trfr,TfR
Number of Launched Drugs:1
Number of Drugs in Clinical Trials:8
Lastest Research Phase:Approved

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Part of Bioactivity data

 Transferrin R SPR

Human Transferrin R Protein, Fc Tag (Cat. No. TFR-H5264) captured on Protein A Chip can bind Human Transferrin, His Tag (Cat. No. TRN-H4229) with an affinity constant of 0.491 μM as determined in a SPR assay (Biacore 8K) (Routinely tested).

 Transferrin R ELISA

Immobilized Biotinylated Rat Transferrin R Protein, His,Avitag (Cat. No. TFR-R82E3) at 5 μg/mL (100 μL/well) on streptavidin (Cat. No. STN-N5116) precoated (0.5 μg/well) plate can bind Mouse Transferrin Protein, Mouse IgG2a Fc Tag (Cat. No. TRN-M525b) with a linear range of 0.2-6 ng/mL (QC tested).

Customer Reviews

Synonym Name



CD antigen CD71 is also known as Transferrin receptor protein 1, TfR, sTfR, p90, TfR1, Trfr, which belongs to the peptidase M28 family and M28B subfamily. CD71 /TFR contains one PA (protease associated) domain. CD71 / TfR1 is required for iron delivery from transferrin to cells. CD71 is a potential new target in cases of human leukomia & lymphoma. CD71 /TFRC / TfR has been shown to interact with GABARAP and HFE.

Clinical and Translational Updates

Public Drug Information

Name Research Code Research Phase Company First Brand Name First Approved Country First Indication First Approved Company First Approved Date Indications Clinical Trials
Pabinafusp alfa JR-141 Approved Jcr Pharmaceuticals Co Ltd Japan Mucopolysaccharidosis II Jcr Pharmaceuticals Co Ltd 2021-03-23 Mucopolysaccharidosis II Details

Clinical Drug Information

Name Research Code Research Phase Company Indications Clinical Trials
Human apotransferrin (Sanquin Blood Supply Foundation) Phase 3 Clinical Sanquin Plasma Products Bv Iron Metabolism Disorders; beta-Thalassemia Details
Lepunafusp alfa JR-171 Phase 2 Clinical Jcr Pharmaceuticals Co Ltd Mucopolysaccharidosis I Details
Trontinemab RO-7126209; RG-6102 Phase 2 Clinical F. Hoffmann-La Roche Ltd Alzheimer Disease Details
PPMX-T003 PPMX-T003 Phase 1 Clinical Perseus Proteomics Inc Polycythemia Vera Details
AOC-1001 Phase 2 Clinical Avidity Biosciences Inc Myotonic Disorders; Genetic Diseases, Inborn; Myotonic Dystrophy; Musculoskeletal Diseases; Muscular Disorders, Atrophic; Muscular Atrophy; Heredodegenerative Disorders, Nervous System; Neuromuscular Diseases; Muscular Diseases; Nervous System Diseases; Muscular Dystrophies; Neurodegenerative Diseases Details
CX-2029 ABBV-2029; ABBV-CX-2029; CX-2029 Phase 2 Clinical Abbvie Inc, Cytomx Therapeutics Inc Head and Neck Neoplasms; Solid tumours; Esophageal Neoplasms; Lymphoma, Large B-Cell, Diffuse; Carcinoma, Non-Small-Cell Lung Details
INA-03 INA03 Phase 1 Clinical Inatherys Leukemia; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Leukemia, Myeloid, Acute Details
DYNE-251 DYNE251 Phase 2 Clinical Dyne Therapeutics Inc Muscular Dystrophy, Duchenne Details

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