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EGF R

EGF R Part of Bioactivity data

EGR-H82E3-Cell-based assay
Evaluation of CAR expression

Cells were transfected with anti-EGFR scFv and cultured for 3 days. Three days post-transfection, 1e6 cells were stained for anti-EGFR scFv with Biotinylated Human EGFR, His,Avitag (Cat. No. EGR-H82E3) followed by PE-conjugated streptavidin. Flow Cytometry assay shows that Biotinylated Human EGFR, His,Avitag (Cat. No. EGR-H82E3) can bind to cells expressing anti-EGFR scFv. The concentration of EGFR used is 0.8 µg/mL. (Data are kindly provided by Guangzhou Bio-gene Technology Co. Ltd.)

EGR-H522a-SPR
Human_FcRn_Heterodimer_Protein_SPR

Immobilized Erbitux on CM5 Chip via anti-human Fc IgG, can bind Human EGF R, His Tag, low endotoxin (Cat.No. EGR-H522a) with an affinity constant of 0.492 nM as determined in SPR assay (Biacore T200) ( Routinely tested).

EGR-HF2H5-ELISA
FITC-Labeled Human EGF R, His TagFITC-Labeled Human EGF R, His Tag (Cat. No. EGR-HF2H5) ELISA bioactivity

Immobilized Cetuximab at 2 μg/mL (100 μL/well) can bind FITC-Labeled Human EGF R, His Tag (Cat. No. EGR-HF2H5) with a linear range of 0.039-0.313 μg/mL (QC tested).

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EGF R Molecule Synonym Name

EGFR,ERBB,ERBB1,HER1,PIG61,mENA

EGF R Molecule Background

The epidermal growth factor receptor (EGFR; ErbB-1; HER1 in humans) is the cell-surface receptor for members of the epidermal growth factor family (EGF-family) of extracellular protein ligands. The epidermal growth factor receptor is a member of the ErbB family of receptors, a subfamily of four closely related receptor tyrosine kinases: EGFR (ErbB-1), HER2/c-neu (ErbB-2), Her 3 (ErbB-3) and Her 4 (ErbB-4). Mutations affecting EGFR expression or activity could result in cancer.

EGF R References

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