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Your Position: Home > EGF R

EGF R

Brief Information

Name:Epidermal growth factor receptor erbB1
Target Synonym:Epidermal Growth Factor Receptor (Avian Erythroblastic Leukemia Viral (V-Erb-B) Oncogene Homolog),Erythroblastic Leukemia Viral (V-Erb-B) Oncogene Homolog (Avian),Avian Erythroblastic Leukemia Viral (V-Erb-B) Oncogene Homolog,Epidermal Growth Factor Receptor Tyrosine Kinase Domain,Cell Proliferation-Inducing Protein 61,Cell Growth Inhibiting Protein 40,EC 2.7.10.1,NISBD2,PIG61,MENA,EC:2.7.10.1,EC 2.7.10,Receptor tyrosine-protein kinase erbB-1,Proto-oncogene c-ErbB-1,Epidermal growth factor recep
Number of Launched Drugs:35
Number of Drugs in Clinical Trials:172
Lastest Research Phase:Approved

Licensing

Project item Indications Research phase Cooperation demands
BHE202201 Esophageal Carcinoma and Pancreatic Cancer Phase III (Esophageal Carcinoma)\ Phase Ib (Pancreatic Cancer) License-out or co-development for the global right and Clinical development in the US or EU (PK and Phase III)

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Part of Bioactivity data

EGR-H82E3-Cell-based assay
Evaluation of CAR expression

Cells were transfected with anti-EGFR scFv and cultured for 3 days. Three days post-transfection, 1e6 cells were stained for anti-EGFR scFv with Biotinylated Human EGFR, His,Avitag (Cat. No. EGR-H82E3) followed by PE-conjugated streptavidin. Flow Cytometry assay shows that Biotinylated Human EGFR, His,Avitag (Cat. No. EGR-H82E3) can bind to cells expressing anti-EGFR scFv. The concentration of EGFR used is 0.8 µg/mL. (Data are kindly provided by Guangzhou Bio-gene Technology Co. Ltd.)

EGR-H522a-SPR
Human_FcRn_Heterodimer_Protein_SPR

Immobilized Erbitux on CM5 Chip via anti-human Fc IgG, can bind Human EGF R, His Tag, low endotoxin (Cat.No. EGR-H522a) with an affinity constant of 0.492 nM as determined in SPR assay (Biacore T200) (Routinely tested).

EGR-H522a-SPR
Human_FcRn_Heterodimer_Protein_SPR

Human EGF R, His Tag, low endotoxin (Cat. No. EGR-H522a) captured on CM5 Chip via anti-His antibody can bind Human EGF, Mouse IgG2a Fc Tag (Cat. No. EGF-H525b) with an affinity constant of 2.76 nM as determined in SPR assay (Biacore T200) (Routinely tested).

Synonym Name

EGFR,ERBB,ERBB1,HER1,PIG61,mENA

Background

The epidermal growth factor receptor (EGFR; ErbB-1; HER1 in humans) is the cell-surface receptor for members of the epidermal growth factor family (EGF-family) of extracellular protein ligands. The epidermal growth factor receptor is a member of the ErbB family of receptors, a subfamily of four closely related receptor tyrosine kinases: EGFR (ErbB-1), HER2/c-neu (ErbB-2), Her 3 (ErbB-3) and Her 4 (ErbB-4). Mutations affecting EGFR expression or activity could result in cancer.

Clinical and Translational Updates

Public Drug Information

Name Research Code Research Phase Company First Brand Name First Approved Country First Indication First Approved Company First Approved Date Indications Clinical Trials
Mouse epidermal growth factor (Hangzhou Tianmushan Pharmaceutical) Approved Hangzhou Tianmushan Pharmaceutical Enterprise Co Ltd 一夫 Wounds and Injuries Details
Recombinant epidermal growth factor drop (Pavay Gene Pharmaceutical) Approved Guilin Huanuowei Gene Pharmaceutical Co Ltd 易贝 Mainland China Corneal Diseases Guilin Huanuowei Gene Pharmaceutical Co Ltd 2002-04-12 Corneal Diseases; Xerophthalmia Details
Recombinant epidermal growth factor (Shanghai Haohai ) Approved Shanghai Haohai Biological Technology Co Ltd 康合素 Mainland China Burns Shanghai Haohai Biological Technology Co Ltd 2001-01-01 Burns Details
Cetuximab biosimilar (CinnaGen) Approved Cinnagen Iran Colorectal Neoplasms Cinnagen 2017-01-01 Colorectal Neoplasms Details
Recombinant Human Epidermal Growth Factor Derivative Eye Drops (Shenzhen Wastin Genetech) Approved Shenzhen Watsin Genetech Ltd 金因舒, GeneSoft Mainland China Corneal Diseases Shenzhen Watsin Genetech Ltd 2004-01-21 Corneal Diseases Details
Recombinant human EGF conjugated vaccine Approved Biotech Pharmaceuticals Co Ltd Carcinoma, Non-Small-Cell Lung Details
Recombinant Human Epidermal Growth Factor Derivative (Shenzhen Wastin Genetech) rEGF Approved Shenzhen Watsin Genetech Ltd 金因肽, GeneTime Mainland China Wounds and Injuries Shenzhen Watsin Genetech Ltd 2001-01-01 Wounds and Injuries Details
Recombinant epidermal growth factor gel (Pavay Gene Pharmaceutical) Approved Guilin Huanuowei Gene Pharmaceutical Co Ltd 易孚 Mainland China Skin Ulcer; Burns Guilin Huanuowei Gene Pharmaceutical Co Ltd 2002-12-23 Skin Ulcer; Burns Details
Epidermal growth factor biosimilar (RAS Lifesciences) Approved Ras Lifesciences India Ras Lifesciences 2012-10-01 Details
Recombinant epidermal growth factor biosimilar (Elea) r-hu-EGF Approved Elea Argentina Diabetic Foot; Burns Elea 2015-01-01 Diabetic Foot; Burns Details
Recombinant epidermal growth factor (Bharat Biotech) REGEN-D 60; REGEN-D 150 Approved Bharat Biotech International Ltd India Diabetic Foot; Burns Bharat Biotech International Ltd 2005-01-01 Diabetic Foot; Burns Details
Recombinant epidermal growth factor (Center for Genetic Engineering and Biotechnology/Praxis Pharmaceuticals) Approved Praxis Pharmaceuticals, Center For Genetic Engineering And Biotechnology Heberprot-P Cuba Diabetic Foot null 2007-09-01 Diabetic Foot Details
PX-070101 PX-070101 Approved Praxis Pharmaceuticals Colombia Diabetic Foot Praxis Pharmaceuticals 2015-07-01 Diabetic Foot Details
Nepidermin DWP-401 Approved Daewoong Pharmaceutical Co Ltd Easyef Egypt Alopecia; Diabetic Foot Daewoong Pharmaceutical Co Ltd 2001-01-01 Diabetic Foot; Alopecia; Dry Eye Syndromes Details
Cetuximab sarotalocan RM-1929; ASP-1929 Approved Aspyrian Therapeutics Akalux Japan Head and Neck Neoplasms Rakuten Medical Inc 2020-09-25 Head and Neck Neoplasms; Squamous Cell Carcinoma of Head and Neck Details
Icotinib Hydrochloride BPI-2009H; BPI-2009C Approved Betta Pharmaceuticals Co Ltd 凯美纳, Conmana Mainland China Carcinoma, Non-Small-Cell Lung Betta Pharmaceuticals Co Ltd 2011-06-07 Breast Neoplasms; Neuroma, Acoustic; Adenocarcinoma; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Brain metastases; Esophageal adenocarcinoma; Lung Neoplasms; Carcinoma, Adenosquamous; Solid tumours; Nasopharyngeal Carcinoma; Psoriasis; Adenocarcinoma of Lung; Neurofibromatosis 2; Bronchial Neoplasms; Esophageal Neoplasms; Stomach Neoplasms Details
Dacomitinib PF-299; PF-804; PF-299804; PF-00299804; PF-00299804-3; PF-00299804-03 Approved Pfizer Inc Vizimpro Mainland China Carcinoma, Non-Small-Cell Lung Pfizer Europe Ma Eeig 2018-09-27 Colorectal Neoplasms; Adenocarcinoma; Neoplasm Metastasis; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Penile Neoplasms; Lung Neoplasms; Esophageal Squamous Cell Carcinoma; Mouth Neoplasms; Head and Neck Neoplasms; Brain Neoplasms; Carcinoma, Large Cell; Liver Diseases; Glioblastoma; Neoplasms; Squamous Cell Carcinoma of Head and Neck; Stomach Neoplasms; Solid tumours Details
Necitumumab LY-3012211; IMC-11F8 Approved Eli Lilly And Company Portrazza Japan Carcinoma, Non-Small-Cell Lung Nippon Kayaku Co Ltd 2015-11-24 Solid tumours; Neoplasms; Colorectal Neoplasms; Carcinoma, Non-Small-Cell Lung; Neoplasm Metastasis Details
Afatinib Dimaleate BIBW-2992; BIBW-2992-MA2 Approved C.H. Boehringer Sohn Ag & Co. Kg Gilotrif, Tomtovok, 吉泰瑞, Tovok, Giotrif Mainland China Carcinoma, Non-Small-Cell Lung Boehringer Ingelheim International Gmbh 2013-07-12 Lymphoma; Prostatic Neoplasms; Brain Neoplasms; Urethral Neoplasms; Colorectal Neoplasms; Urologic Neoplasms; Ureteral Neoplasms; Carcinoma, Squamous Cell; Lung Neoplasms; Breast Neoplasms; Uterine Neoplasms; Glioma; Esophageal Squamous Cell Carcinoma; Gallbladder Neoplasms; Neoplasm Metastasis; Carcinoma, Non-Small-Cell Lung; Adenocarcinoma; Hematologic Neoplasms; Liver Diseases; Urinary Bladder Neoplasms; Chordoma; Multiple Myeloma; Neuroectodermal Tumors; Glioblastoma; Neoplasms; Neoplasms, Squamous Cell; Renal Insufficiency; Squamous Cell Carcinoma of Head and Neck; Esophageal Neoplasms; Stomach Neoplasms; Rhabdomyosarcoma; Head and Neck Neoplasms; Solid tumours Details
Erlotinib Hydrochloride CP-358774-01; RO-0508231; NSC-718781; CP-358774; RG-1415; OSI-774; R-1415 Approved Genentech Inc Tarceva, 特罗凯 Japan Carcinoma, Non-Small-Cell Lung Chugai Pharmaceutical Co Ltd 2004-11-18 Urologic Neoplasms; Brain metastases; Esophageal adenocarcinoma; Lung Neoplasms; Lip Neoplasms; Mouth Neoplasms; Carcinoma, Mucoepidermoid; Bile Duct Neoplasms; Adenocarcinoma, Bronchiolo-Alveolar; Oropharyngeal Neoplasms; Neuroectodermal Tumors, Primitive; Ureteral Neoplasms; Astrocytoma; Glioma; Gliosarcoma; Colorectal Neoplasms; Psoriasis; Osteosarcoma; Sarcoma; Cholangiocarcinoma; Metaplasia; Urethral Neoplasms; Neuroblastoma; Brain Neoplasms; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Adenocarcinoma; Carcinoma, Hepatocellular; Carcinoma, Endometrioid; Melanoma; Neoplasms, Germ Cell and Embryonal; Breast Neoplasms, Male; Meningioma; Precancerous Conditions; Neoplasm Metastasis; Uterine Cervical Neoplasms; Tongue Neoplasms; Prostatic Neoplasms; Laryngeal Neoplasms; Adenomatous Polyps; Lymphoma; Gallbladder Neoplasms; Esophageal Squamous Cell Carcinoma; Carcinoma, Squamous Cell; Adenocarcinoma, Mucinous; Paranasal Sinus Neoplasms; Neoplasms, Unknown Primary; Endometrial Neoplasms; Fallopian Tube Neop Details
Cetuximab IMC-C255; BMS-564717; EMD-271786; C-255; GT-MAB-5.2; ch-225; LY-2939777; NSC-714692 Approved Bristol-Myers Squibb Company, Eli Lilly And Company, Merck Serono 爱必妥, Erbitux Mainland China Squamous Cell Carcinoma of Head and Neck Merck Serono Co Ltd 2004-02-12 Endometrial Neoplasms; Oropharyngeal Neoplasms; Peritoneal Neoplasms; Neuralgia; Fallopian Tube Neoplasms; Lung Neoplasms; Esophageal Squamous Cell Carcinoma; Laryngeal Neoplasms; Carcinoma, Squamous Cell; Colorectal Neoplasms; Adenocarcinoma, Mucinous; Neoplasm Metastasis; Carcinoma, Non-Small-Cell Lung; Precancerous Conditions; Complex Regional Pain Syndromes; Carcinoma, Hepatocellular; Gastrointestinal Neoplasms; Colonic Neoplasms; Head and Neck Neoplasms; Neoplastic Cells, Circulating; Liver Neoplasms; Solid tumours; Stomach Neoplasms; Esophageal Neoplasms; Pain; Squamous Cell Carcinoma of Head and Neck; Ovarian Neoplasms; Neoplasms; Pancreatic Neoplasms; Hypopharyngeal Neoplasms; Neoplasms, Squamous Cell; Carcinoma, Adenoid Cystic; Nasopharyngeal Carcinoma; Sarcoma Details
Lapatinib Ditosylate Hydrate GW-572016; GW-572016F; GW-2016 Approved Glaxosmithkline Plc, Novartis Pharma Ag Tykerb, Tyverb, 泰立沙, Tykerb/Tyverb Mainland China Breast Neoplasms Glaxosmithkline Ag 2007-03-13 Neoplasms, Gonadal Tissue; Carcinoma, Acinar Cell; Carcinoma, Mucoepidermoid; Colorectal Neoplasms; Astrocytoma; Gliosarcoma; Bile Duct Neoplasms; Carcinoma, Squamous Cell; Lymphoma; Glioma; Brain metastases; Lung Neoplasms; Endometrial Neoplasms; Brain Neoplasms; Laryngeal Neoplasms; Gallbladder Neoplasms; Adenocarcinoma; Uterine Cervical Neoplasms; Carcinoma, Hepatocellular; Neoplasm Metastasis; Tongue Neoplasms; Melanoma; Breast Neoplasms, Male; Carcinoma, Non-Small-Cell Lung; Neuroma, Acoustic; Pancreatic Neoplasms; Ovarian Neoplasms; Head and Neck Neoplasms; Ependymoma; Liver Neoplasms; Medulloblastoma; Stomach Neoplasms; Esophageal Neoplasms; Abdominal Neoplasms; Squamous Cell Carcinoma of Head and Neck; Carcinoma, Renal Cell; Carcinoma; Carcinoma, Ovarian Epithelial; Solid tumours; Carcinoma, Verrucous; Glioblastoma; Salivary Gland Neoplasms; Neoplasms; Neurofibromatosis 2; Urinary Bladder Neoplasms; Carcinoma, Adenoid Cystic; Central Nervous System Neoplasms; Oligodendroglioma; Breast Neoplasms; Prost Details
Gefitinib ZD-1839 Approved Astrazeneca Pharmaceutical Co Ltd 易瑞沙, Iressa EU Carcinoma, Non-Small-Cell Lung Astrazeneca Ab 2002-07-05 Fallopian Tube Neoplasms; Gastrinoma; Prostatic Neoplasms; Brain Neoplasms; Urethral Neoplasms; Breast Neoplasms; Astrocytoma; Gliosarcoma; Colorectal Neoplasms; Adenocarcinoma, Bronchiolo-Alveolar; Carcinoma, Mucoepidermoid; Lung Neoplasms; Neoplasms, Neuroepithelial; Glioma; Carcinoma, Adenosquamous; Endometrial Neoplasms; Carcinoma, Squamous Cell; Leukemia, Myeloid, Acute; Brain metastases; Carcinoma, Non-Small-Cell Lung; Neoplasms, Germ Cell and Embryonal; Uterine Cervical Neoplasms; Breast Neoplasms, Male; Gastrointestinal Neoplasms; Carcinoma, Hepatocellular; Somatostatinoma; Neoplasm Metastasis; Adenocarcinoma; Glioblastoma; Liver Neoplasms; Solid tumours; Kidney Neoplasms; Ovarian Neoplasms; Carcinoma, Islet Cell; Vipoma; Insulinoma; Carcinoid Tumor; Abdominal Neoplasms; Carcinoma, Renal Cell; Esophageal Neoplasms; Carcinoma; Stomach Neoplasms; Head and Neck Neoplasms; Skin Neoplasms; Neoplasms; Carcinoma, Transitional Cell; Adenocarcinoma of Lung; Small Cell Lung Carcinoma; Salivary Gland Neoplasms; Details
Osimertinib Mesylate AZD-9291; RDL94R2A16; AZD-9291 Mesylate; AZD9291 Approved Astrazeneca Pharmaceutical Co Ltd 泰瑞沙, Tagrisso Mainland China Carcinoma, Non-Small-Cell Lung Astrazeneca Ab 2015-11-13 Uterine Neoplasms; Prostatic Neoplasms; Breast Neoplasms; Meningeal Neoplasms; Colorectal Neoplasms; Carcinoma, Squamous Cell; Lung Neoplasms; Brain metastases; Esophageal adenocarcinoma; Cholangiocarcinoma; Lymphoma; Glioma; Endometrial Neoplasms; Thyroid Neoplasms; Adenocarcinoma; Carcinoma, Non-Small-Cell Lung; Uterine Cervical Neoplasms; Melanoma; Adenocarcinoma of Lung; Liver Neoplasms; Ovarian Neoplasms; Squamous Cell Carcinoma of Head and Neck; Carcinoma, Renal Cell; Rectal Neoplasms; Stomach Neoplasms; Esophageal Neoplasms; Neoplasms; Solid tumours; Carcinoma, Ovarian Epithelial; Carcinoma, Transitional Cell; Pancreatic Neoplasms; Skin Neoplasms; Colonic Neoplasms; Glioblastoma; Multiple Myeloma; Urinary Bladder Neoplasms Details
Brigatinib AP-26113 Approved Ariad, Takeda Pharmaceutical Co Ltd Alunbrig Mainland China Carcinoma, Non-Small-Cell Lung Takeda (China) International Trading Co Ltd 2017-04-28 Solid tumours; Ependymoma; Carcinoma; Neoplasms; Neurofibromatosis 2; Myofibroma; Lymphoma, Large-Cell, Anaplastic; Granuloma, Plasma Cell; Lung Neoplasms; Brain metastases; Carcinoma, Non-Small-Cell Lung; Sarcoma, Kaposi; Meningioma; Neurilemmoma; Neuroma, Acoustic Details
Pyrotinib Maleate HTI-1001; SHR-1258; BLTN Approved Jiangsu Hengrui Medicine Co Ltd 艾瑞妮 Mainland China Breast Neoplasms Jiangsu Hengrui Medicine Co Ltd 2018-08-12 Solid tumours; Biliary Tract Neoplasms; Esophageal Neoplasms; Stomach Neoplasms; Adenocarcinoma of Lung; Neoplasms; Breast Neoplasms; Bile Duct Neoplasms; Metastatic breast cancer; Lung Neoplasms; Carcinoma, Non-Small-Cell Lung; Gastrointestinal Neoplasms Details
Amivantamab JNJ-372; JNJ-61186372 Approved Janssen Global Services Llc, Genmab A/S RYBREVANT Canada Carcinoma, Non-Small-Cell Lung Janssen Inc 2021-05-21 Solid tumours; Esophageal Neoplasms; Stomach Neoplasms; Colorectal Neoplasms; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung Details
Panitumumab ABX-0303; E7.6.3; AMG-954; ABX-EGF; ABX-10221 Approved Amgen Inc Vectibix Japan Colorectal Neoplasms Takeda 2006-09-27 Salivary Gland Neoplasms; Gastrointestinal Neoplasms; Exanthema; Carcinoma, Non-Small-Cell Lung; Neoplasm Metastasis; Glioma; Carcinoma, Squamous Cell; Lung Neoplasms; Adenoma, Pleomorphic; Colorectal Neoplasms; Brain Neoplasms; Prostatic Neoplasms; Kidney Neoplasms; Malignant Carcinoid Syndrome; Pancreatic Neoplasms; Colonic Neoplasms; Neoplasms; Squamous Cell Carcinoma of Head and Neck; Carcinoma, Renal Cell; Carcinoma; Rectal Neoplasms; Esophageal Neoplasms; Head and Neck Neoplasms; Solid tumours Details
Neratinib Maleate CAN-030; HKI-272; PF-0528767; WAY-179272; PB-272 Approved Pfizer Pharmaceuticals Ltd (China) Nerlynx, 贺俪安 Mainland China Breast Neoplasms Excella Gmbh & Co Kg 2017-07-17 Solid tumours; Neoplasms; Prostatic Neoplasms, Castration-Resistant; Breast Neoplasms; Prostatic Neoplasms; Hepatic Insufficiency; Colorectal Neoplasms; Lung Neoplasms; Metastatic breast cancer; Brain metastases; Carcinoma, Non-Small-Cell Lung Details
Lazertinib YH-25448; JNJ-73841937; JNJ-1937; GNS-1480 Approved Oscotec Inc, Janssen Biotech Inc, Yuhan Corp Leclaza South Korea Carcinoma, Non-Small-Cell Lung Yuhan Corp 2021-01-18 Hepatic Insufficiency; Carcinoma, Non-Small-Cell Lung Details
Nimotuzumab OSAG-10; KI-0502; KI-0501; DE-766; YMB-1000; OSAG-101; h-R3; TheraCIMh-R3 Approved Center Of Molecular Immunology, Cimym Biosciences Theraloc, BIOMAb-EGFR, TheraCIM, 泰欣生, CIMAher Mainland China Nasopharyngeal Neoplasms Biotech Pharmaceuticals Co Ltd 2006-07-21 Solid tumours; Head and Neck Neoplasms; Squamous Cell Carcinoma of Head and Neck; Anus Neoplasms; Neoplasms; Nasopharyngeal Neoplasms; Pancreatic Neoplasms; Pancreatic neuroendocrine tumors (pNET); Nasopharyngeal Diseases; Nasopharyngeal Carcinoma; Esophageal Squamous Cell Carcinoma; Glioma; Carcinoma, Squamous Cell; Carcinoma, Non-Small-Cell Lung; Uterine Cervical Neoplasms; Esophageal Diseases Details

Clinical Drug Information

Name Research Code Research Phase Company Indications Clinical Trials
Humanized anti-EGFR monoclonal antibody (Hualan Biological Engineering/Henan shengming biotechnology) Phase 2 Clinical Henan Shengming Biotechnology Research Institute Co Ltd, Hualan Genetic Engineering Co Ltd Colorectal Neoplasms Details
WTS-004 WTS-004 Phase 1 Clinical Hangzhou Wutong Tree Pharmaceutical Co Ltd Carcinoma, Non-Small-Cell Lung Details
JRF-103 JRF103; JRF-103 Phase 2 Clinical Shenzhen Jinrui Foundation Biotechnology Co Ltd Solid tumours Details
Anti-CTLA-4/PD-1 expressing EGFR-CAR-T Phase 2 Clinical Shanghai Cell Therapy Research Institute Solid tumours Details
EGFR IL12 CART Phase 1 Clinical Shenzhen Prekin Biopharmaceutical Co Ltd Colorectal Neoplasms Details
Losatuxizumab vedotin ABBV221; ABBV-221 Phase 1 Clinical Abbvie Inc Neoplasms Details
Cetuximab biosimilar (Enzene Biosciences) Clinical Enzene Biosciences Ltd Carcinoma, Squamous Cell Details
PB-357 PB-357 Phase 1 Clinical Pfizer Inc Neoplasms Details
SGT-210 SGT-210 Phase 1 Clinical Sol Gel Technologies Pte Ltd Keratosis Details
Cetuximab I-131 (Pacific Meinuoke) Clinical Jiangsu Pacific-Meinuoke Bio-Pharmaceutical Co Ltd Colorectal Neoplasms Details
KSP-QRH-E3-IRDye800 Phase 1 Clinical University Of Michigan Cholangiocarcinoma Details
Betatinib TL-512 Phase 1 Clinical Aspedia Llc, Suzhou Teligene Ltd Carcinoma, Non-Small-Cell Lung Details
Cetuximab biobetter (Mabtech/Sorrento) STI-001 Phase 3 Clinical Taizhou Maibo Taike Biotechnology Co Ltd, Shanghai Biomabs Pharmaceuticals Co Ltd Colorectal Neoplasms Details
EGFRvIII-CAR Phase 1 Clinical Duke University Medical Center Glioblastoma Details
Recombinant chimeric anti-EGFR monoclonal antibody (Qilu Pharmaceutical) QL-1105 Phase 1 Clinical Qilu Pharmaceutical Co Ltd Solid tumours Details
Cetuximab biosimilar (AlphaMab) KN-005 Phase 3 Clinical Head and Neck Neoplasms; Anus Neoplasms; Urinary Bladder Neoplasms; Colorectal Neoplasms Details
HER-1 vaccine (Center of Molecular Immunology) HER1-ECD; HER1-VSSP; HER-1-ECD-VSSP Phase 2 Clinical Center Of Molecular Immunology Neoplasms Details
Durvalumab/Gefitinib Phase 2 Clinical Medimmune Carcinoma, Non-Small-Cell Lung Details
Anti-EGFR CAR T-cell therapy (Seattle Children's Hospital) EGFR-806 Phase 1 Clinical Seattle Children'S Hospital Central Nervous System Neoplasms Details
Nimotuzumab biosimilar (IBC Generium) Phase 3 Clinical International Biotechnology Center Generium Llc Head and Neck Neoplasms Details
BC-3448 BC-3448; BC3448 Phase 1 Clinical Wuxi Zhikang Hongyi Biological Technology Co Ltd Solid tumours Details
Recombinant anti-InE monoclonal antibody CmAb-(IL10)2 Phase 1 Clinical Dingfu Biotarget Co Ltd Solid tumours Details
BEBT-109 BEBT-109 Phase 2 Clinical Guangzhou BeBetter Medicine Technology Co Carcinoma, Non-Small-Cell Lung Details
SMET-12 SMET-12 Phase 1 Clinical Zhejiang Shimai Pharmaceutical Co Ltd Solid tumours Details
Sirotinib Maleate XZP-5491 Phase 1 Clinical Shandong Xuanzhu Pharmaceutical Technology Co Ltd Stomach Neoplasms; Carcinoma, Squamous Cell; Carcinoma, Non-Small-Cell Lung Details
Puvitinib Phase 1 Clinical Suzhou Teligene Ltd Solid tumours Details
KY-1701 KY-1701 Phase 1 Clinical Jiangsu Kanion Pharmaceutical Co Ltd Breast Neoplasms Details
Epertinib S-222611 Phase 2 Clinical Shionogi & Co Ltd Neoplasms Details
WSD-0922 WSD0922; WSD-0922 Phase 1 Clinical Vision Biological Tech (Hefei) Co Ltd Glioblastoma; Glioma Details
Mefatinib Phase 3 Clinical Suzhou Maitai Bio-Technology Co Ltd Solid tumours; Carcinoma, Non-Small-Cell Lung Details
CMAB-017 CMAB-017 Phase 1 Clinical Taizhou Mabtech Pharmaceutical Co Ltd Solid tumours Details
Anti-CD3/anti-EGFR -activated T cells (Barbara Ann Karmanos Cancer Institute) Barbara Ann Karmanos Cancer Institute, University Of Virginia Details
ZZ-06 ZZ-06 Phase 1 Clinical Changchun Intellicrown Pharmaceutical Co Ltd Solid tumours Details
ABBV-637 ABBV-637 Abbvie Inc Details
FWD1509 MsOH FWD1509 MsOH Phase 1 Clinical Shenzhen Forward Pharmaceuticals Co Ltd Carcinoma, Non-Small-Cell Lung Details
[111In] Panitumumab Stanford University Details
BB-1705 BB-1705 Phase 1 Clinical Baili Sikang Biomedicine (Hangzhou) Co Ltd Solid tumours; Neoplasms; Neoplasm Metastasis Details
EGFR/B7H3 CAR-T EGFR/B7H3 CAR-T Second Affiliated Hospital Of Guangzhou Medical University Details
JMT101 JMT-101 Phase 3 Clinical Shanghai Jinmante Biological Technology Co Ltd Solid tumours; Carcinoma, Non-Small-Cell Lung Details
MP-412 AV-412; MP-412 Mitsubishi Tanabe Pharma Details
Recombinant anti-EGFR chimeric monoclonal antibody (Shanghai CP Guojian) CPGJ-602; 602; CPGJ602; CPGJ 602 Phase 2 Clinical Shanghai Cp Guojian Pharmaceutical Co Ltd Colorectal Neoplasms Details
Cimaglermin alfa CGF-2 Ludwig Institute For Cancer Research Details
TAK-285 TAK-285 Takeda Details
Immunomodulatory progenitor cell therapy (Celixir) Phase 3 Clinical Celixir Cardiomyopathies Details
BB-101 (Blue Blood Biotech/National Cheng Kung University) BB-101 National Cheng Kung University, Blue Blood Biotech Corp Details
Cetuximab biosimilar (R-Pharm) RPH-002 Phase 3 Clinical R-Pharm Head and Neck Neoplasms Details
Nimotuzumab biosimilar (El Kendi Pharmaceuticals Manufacturing) El Kendi Pharmaceuticals Details
TTI-1612 TTI-1612 Details
TQB-3456 TQB-3456 Phase 1 Clinical Jiangsu Chia Tai-Tianqing Pharmaceutical Co Ltd, Lianyungang Runzhong Pharmaceutical Co Ltd, Centaurus Biopharma Co Ltd Carcinoma, Non-Small-Cell Lung Details
PF-06459988 PF-6459988; PF-06459988 Pfizer Pharmaceuticals Ltd (China) Details
EMD 55900 EMD-55900 Merck Serono Details
Mavelertinib PF-7775; PFE-X775; PF6747775; PF-06747775 Pfizer Pharmaceuticals Ltd (China) Details
MP-0274 DARPin-41; SPA-28; CME-114; CME-115; CME-118; CME-119; MP-0274 Molecular Partners Ag Details
Olafertinib CK-101; RX-518; CS-2481; EGFR-IN-3 Phase 3 Clinical Suzhou Neupharma Co Ltd Carcinoma, Non-Small-Cell Lung Details
Sutetinib Maleate Phase 2 Clinical Jiangsu Maidu Pharmaceutical R & D Co Ltd, Jiangsu Suzhong Pharma Group Co Ltd Solid tumours; Carcinoma, Non-Small-Cell Lung Details
BPI-15086 BPI-15000; BPI-15086 Phase 1 Clinical Betta Pharmaceuticals Co Ltd Carcinoma, Non-Small-Cell Lung Details
Nazartinib EGF-816; EGFRmut-TKI EGF816 Phase 2 Clinical Novartis Pharma Ag Bronchial Neoplasms; Triple Negative Breast Neoplasms; Colorectal Neoplasms; Lung Neoplasms; Carcinoma, Non-Small-Cell Lung; Adenocarcinoma Details
GC-1118A GC-1118; GC-1118A Phase 2 Clinical Korean Green Cross Corp Solid tumours; Stomach Neoplasms; Colorectal Neoplasms; Neoplasm Metastasis Details
IAE-0972 IAE-0972 Phase 2 Clinical Shenghe (China) Biopharmaceutical Co Ltd Solid tumours Details
Recombinant anti-EGFR chimeric antibody (Harbin Pharmaceutical) Phase 1 Clinical Harbin Pharmaceutical Group Holding Co Ltd Colorectal Neoplasms Details
Cetuximab biosimilar (Humanwell Healthcare) Phase 1 Clinical Humanwell Healthcare (Group) Co Ltd Colorectal Neoplasms Details
Neptinib Di-P-methylbenzenesulfonate Phase 1 Clinical Shenzhen Neptunus Pharmaceutical Research Institute Co Ltd Stomach Neoplasms; Breast Neoplasms; Colorectal Neoplasms; Carcinoma, Non-Small-Cell Lung Details
LY-01010 LY-01010 Phase 1 Clinical Luye Pharma Group Ltd Breast Neoplasms Details
HS-10376 Phase 2 Clinical Jiangsu Hansoh Pharmaceutical Group Co Ltd Solid tumours; Carcinoma, Non-Small-Cell Lung Details
Selatinib Ditosilate QLNC-120 Phase 2 Clinical Qilu Antibiotics (Linyi) Pharmaceutical Co Ltd, Qilu Pharmaceutical Co Ltd Breast Neoplasms Details
Allitinib Tosylate AST-6; ALS-1306; AST-1306 Phase 2 Clinical Shanghai Allist Pharmaceutical Technology Co Ltd Breast Neoplasms; Carcinoma, Non-Small-Cell Lung Details
AMX-3009 Maleate AMX-3009; AMX3009马来酸 Phase 1 Clinical Anrun Medicine Technology (Suzhou) Co Ltd Solid tumours; Stomach Neoplasms; Pancreatic Neoplasms; Breast Neoplasms Details
EG-007 EG-007 Phase 3 Clinical Evergreen Therapeutics Inc Endometrial Neoplasms Details
CKD-702 Phase 1 Clinical Chong Kun Dang Pharmaceutical Corp Carcinoma, Non-Small-Cell Lung Details
NIP-142 NIP-142 Phase 1 Clinical Carcinoma, Non-Small-Cell Lung Details
Recombinant chimeric anti-EGFR monoclonal antibody (Zhejiang Xinwei Shengke Biotechnology) Phase 1 Clinical Zhejiang Xinweishengke Biotechnology Co Ltd Esophageal Neoplasms Details
ORIC-114 ORIC-114 Phase 1 Clinical Voronoi Solid tumours; Carcinoma, Non-Small-Cell Lung Details
Double-deleted Vaccinia Virus Plus CD/ SMR JX-929; vvDD-CDSR Phase 1 Clinical Sillajen Inc Liver Neoplasms; Squamous Cell Carcinoma of Head and Neck; Pancreatic Neoplasms; Breast Neoplasms; Colorectal Neoplasms; Melanoma Details
Simotinib Hydrochloride AL-6802; SIM-6802 Phase 1 Clinical Jiangsu Simcere Pharmaceutical Co Ltd, Advenchen Laboratories Llc Carcinoma, Non-Small-Cell Lung Details
ZN-e4 ZN-e4; KP-673 Phase 2 Clinical Zentalis Pharmaceuticals LLC, Zeno Pharma Carcinoma, Non-Small-Cell Lung Details
BBT-176 BBT-176 Phase 2 Clinical Bridge Biotherapeutics Inc Carcinoma, Non-Small-Cell Lung Details
Anti-EGFR-IL-dox (Swiss Group for Clinical Cancer Research) Phase 2 Clinical Schweizerische Arbeitsgemeinschaft Für Klinische Krebsforschung Breast Neoplasms Details
Hemay-020 Hemay-020 Phase 1 Clinical Tianjin Hemay Pharmaceutical Co Ltd, Hainan General Sanyang Pharmaceutical Co Ltd Solid tumours; Carcinoma, Non-Small-Cell Lung Details
Anti-EGFR-bispecific antibody armed activated T-cell therapy (Memorial Sloan Kettering Cancer Center) Phase 1 Clinical Memorial Sloan Kettering Cancer Center Pancreatic Neoplasms Details
C225-ILS-DOX C225-ILs-dox Phase 2 Clinical Universitaetsspitals Basel Breast Neoplasms Details
D2C7-based immunotoxins (Duke University) D2C7-IT; scds-D2C7 -PE38KDEL; D2C7-(scdsFv)-PE38 KDEL Phase 1 Clinical Istari Oncology Inc, Duke University Glioma Details
ABY-029 ABY-029 Phase 1 Clinical Dartmouth College, Affibody Ab, Li-Cor Bioscience Head and Neck Neoplasms; Sarcoma; Glioma Details
Autologous EGFR-CAR T cells (Bio-gene) Phase 1 Clinical Sun Yat-Sen University, Guangzhou Bio-Gene Technology Co Ltd Carcinoma, Non-Small-Cell Lung Details
M-1231 M-1231 Phase 1 Clinical Emd Serono Research & Development Institute Inc, Merck Serono Solid tumours; Esophageal Neoplasms; Carcinoma, Non-Small-Cell Lung Details
Anti-EGFR CAR-T cell therapy (Beijing Pregene) Phase 2 Clinical Shenzhen Prekin Biopharmaceutical Co Ltd Colorectal Neoplasms Details
AP-L1898 JS111; AP-L1898; WJ-002 Phase 2 Clinical Suzhou Junjing Biomedical Technology Co Ltd, Wigen Biomedicine technology (Shanghai) Co Ltd, Shanghai Junshi Biosciences Co Ltd Lung Neoplasms; Carcinoma, Non-Small-Cell Lung Details
TAK-186 EGFR x CD3 COBRA; MVC-101; TAK-186 Phase 2 Clinical Takeda Pharmaceutical Co Ltd Solid tumours; Squamous Cell Carcinoma of Head and Neck; Colorectal Neoplasms; Carcinoma, Non-Small-Cell Lung Details
E-EDV-D682 PNU-15982; E-EDV-D682; EGFR-EDV-PNU-15982 Phase 2 Clinical Engeneic Ltd Pancreatic Neoplasms Details
Antibody-drug nanocell conjugates (EnGeneIC) EGFR-EDV-RRM1; EGFR-EDV-PLK; EGFR-EDV-Dox Phase 1 Clinical Engeneic Ltd Glioblastoma Details
H-002 H-002 Phase 2 Clinical Neoplasms; Carcinoma, Non-Small-Cell Lung Details
DBPR-112 DBPR-112; ABT-101 Phase 2 Clinical National Health Research Institutes Head and Neck Neoplasms; Solid tumours; Lung Neoplasms; Carcinoma, Non-Small-Cell Lung Details
YK-029A YK-029A Phase 1 Clinical Hainan Yuekang Biomedicine Co Ltd Carcinoma, Non-Small-Cell Lung Details
ZSP-0391 ZSP-0391 Phase 1 Clinical Wuxi Apptec Co Ltd, Guangdong Zhongsheng Pharmaceutical Co Ltd Carcinoma, Non-Small-Cell Lung Details
SYN-004 (Synermore Biologics) LR-004; SYN-004 Phase 1 Clinical Lonn Ryonn Pharma Ltd, Synermore Biologics (Suzhou) Co Ltd Solid tumours; Carcinoma; Lymphoma, Large B-Cell, Diffuse; Colorectal Neoplasms Details
PLB-1004 PLB-1004 Phase 1 Clinical Beijing Anshi Biotechnology Co Ltd Carcinoma, Non-Small-Cell Lung Details
REGN-7075 REGN-7075 Phase 2 Clinical Regeneron Pharmaceuticals Inc Solid tumours; Neoplasms Details
BLU-451 BLU-451 Phase 2 Clinical Blueprint Medicines Corp Carcinoma, Bronchogenic; Bronchial Neoplasms; Carcinoma; Respiratory Tract Diseases; Neoplasms; Lung Diseases; Respiratory Tract Neoplasms; Neoplasms, Nerve Tissue; Lung Neoplasms; Carcinoma, Non-Small-Cell Lung; Adenocarcinoma Details
GB-263 GB-263; GB-263T Phase 2 Clinical Genor Biopharma Co Ltd Solid tumours; Neoplasms; Carcinoma, Non-Small-Cell Lung Details
Demupitamab SCT-200 Phase 2 Clinical SinoCelltech Ltd Solid tumours; Head and Neck Neoplasms; Biliary Tract Neoplasms; Ovarian Neoplasms; Stomach Neoplasms; Squamous Cell Carcinoma of Head and Neck; Carcinoma, Renal Cell; Carcinoma; Pancreatic Neoplasms; Neoplasms; Triple Negative Breast Neoplasms; Colorectal Neoplasms; Esophageal Squamous Cell Carcinoma; Gallbladder Neoplasms; Carcinoma, Non-Small-Cell Lung; Carcinoma, Hepatocellular Details
Sapitinib AZD-8931 Phase 2 Clinical Astrazeneca Pharmaceutical Co Ltd Solid tumours; Stomach Neoplasms; Esophageal Neoplasms; Neoplasms; Breast Neoplasms; Colorectal Neoplasms; Carcinoma, Non-Small-Cell Lung; Neoplasm Metastasis Details
TQ-B3395 TQ-B3395; TQ-B-3395 Phase 1 Clinical Centaurus Biopharma Co Ltd, Jiangsu Chia Tai-Tianqing Pharmaceutical Co Ltd Neoplasms; Breast Neoplasms Details
Cetuximab biosimilar (Shanghai Zhangjiang Biotechnology) STI-001; CMAB-009 Phase 3 Clinical Shanghai Zhangjiang Biotechnology Co Ltd Neoplasms; Colorectal Neoplasms Details
TQB3804 TQB-3804 Phase 1 Clinical Jiangsu Chia Tai-Tianqing Pharmaceutical Co Ltd Solid tumours; Neoplasms; Neoplasm Metastasis; Carcinoma, Non-Small-Cell Lung Details
Cetuximab biosimilar (Guilin Sanjin) CDP-1; BC-001 Phase 1 Clinical Dragonboat Biopharmaceutical, Guilin Sanjin Pharmaceutical Co Ltd Solid tumours; Neoplasms; Colorectal Neoplasms Details
CART-EGFR-IL13Ra2 CART-EGFR-IL13Ra2; CAR-T-EGFR-IL-13-Ra-2 Phase 1 Clinical University Of Pennsylvania Glioblastoma Details
Futuximab/Modotuximab 992-and-1024; Sym-004; S95026; S-95026 Phase 3 Clinical Symphogen A/S Solid tumours; Carcinoma; Squamous Cell Carcinoma of Head and Neck; Colorectal Neoplasms; Glioma Details
QLH-11811 QLH-11811; QLH11811 Phase 1 Clinical Qilu Pharmaceutical Co Ltd Carcinoma, Non-Small-Cell Lung Details
BNA-035 BNA-035 Phase 1 Clinical Binacea Pharma Inc Solid tumours Details
BLU-701 BLU 701; BLU-701 Phase 2 Clinical Blueprint Medicines Corp Carcinoma, Bronchogenic; Carcinoma; Thoracic Neoplasms; Bronchial Neoplasms; Respiratory Tract Diseases; Neoplasms; Lung Diseases; Respiratory Tract Neoplasms; Neoplasms, Nerve Tissue; Lung Neoplasms; Carcinoma, Non-Small-Cell Lung; Adenocarcinoma Details
NRC-2694 NRC-2694; NRC-2694A; NRC-2694-A Phase 2 Clinical Natco Pharma Carcinoma; Squamous Cell Carcinoma of Head and Neck Details
Bafisontamab FIT-013a; EMB-01 Phase 2 Clinical Shanghai Epimab Biotherapeutics, Inc Liver Neoplasms; Biliary Tract Neoplasms; Carcinoid Tumor; Stomach Neoplasms; Neoplasms; Digestive System Neoplasms; Colorectal Neoplasms; Lung Neoplasms; Carcinoma, Non-Small-Cell Lung; Neoplasm Metastasis; Gastrointestinal Neoplasms; Carcinoma, Hepatocellular Details
Cetuximab biosimilar (AMPO Biotechnology) Phase 3 Clinical Ampo Biotechnology Inc Colorectal Neoplasms Details
MCLA-129 MCLA-129 Phase 2 Clinical Merus Nv Solid tumours; Head and Neck Neoplasms; Stomach Neoplasms; Colorectal Neoplasms; Carcinoma, Non-Small-Cell Lung Details
AFM-24 AFM-24 Phase 2 Clinical Affimed Solid tumours Details
[89Zr]Panitumumab (University of Alabama at Birmingham) Phase 1 Clinical University Of Alabama At Birmingham Squamous Cell Carcinoma of Head and Neck; Colonic Neoplasms; Pancreatic Neoplasms Details
Cetuximab biosimilar (Kelun Group) KL-A140; KLA140; A-140; KL-140; KLA-140 Phase 3 Clinical Sichuan Kelun Pharmaceutical Co Ltd Rectal Neoplasms; Cholangiocarcinoma; Colorectal Neoplasms; Adenocarcinoma Details
BPI-361175 BPI-361175 Phase 2 Clinical Betta Pharmaceuticals Co Ltd Carcinoma, Non-Small-Cell Lung Details
TAS-6417 CLN-081; TAS-6417 Phase 2 Clinical Taiho Pharmaceutical Co Ltd Carcinoma, Non-Small-Cell Lung Details
Tarloxotinib Bromide PR-610; TH-4000; SN-33999 Phase 2 Clinical Threshold Solid tumours; Carcinoma, Non-Small-Cell Lung Details
Petosemtamab MCLA-158 Phase 1 Clinical Merus Nv Neoplasms; Colorectal Neoplasms Details
Pimurutamab HLX-07 Phase 2 Clinical Shanghai Henlius Biotech Co Ltd Solid tumours; Carcinoma, Renal Cell; Squamous Cell Carcinoma of Head and Neck; Stomach Neoplasms; Esophageal Neoplasms; Neoplasms; Small Cell Lung Carcinoma; Carcinoma, Adenosquamous; Nasopharyngeal Carcinoma; Colorectal Neoplasms; Carcinoma, Squamous Cell; Esophageal Squamous Cell Carcinoma; Lung Neoplasms; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung Details
HS-10375 HS-10375 Phase 2 Clinical Jiangsu Hansoh Pharmaceutical Group Co Ltd Carcinoma, Non-Small-Cell Lung Details
BDTX-1535 BDTX-1535 Phase 1 Clinical Black Diamond Therapeutics Inc Glioblastoma; Carcinoma, Non-Small-Cell Lung Details
MRG003 MRG-003 Phase 2 Clinical Shanghai Miracogen Inc Head and Neck Neoplasms; Biliary Tract Neoplasms; Solid tumours; Stomach Neoplasms; Esophageal Neoplasms; Squamous Cell Carcinoma of Head and Neck; Nasopharyngeal Carcinoma; Colorectal Neoplasms; Bile Duct Neoplasms; Carcinoma, Non-Small-Cell Lung Details
DWP-708 DWP-708 Phase 2 Clinical Daewoong Pharmaceutical Co Ltd Acneiform Eruptions Details
TAVO-412 TAVO-412 Phase 1 Clinical Tavotek Biotherapeutics (Hong Kong) Ltd Neoplasms Details
Tesevatinib XL-647; KD-020; KD-019; EXEL-7647 Phase 2 Clinical Exelixis Inc Neoplasms; Glioblastoma; Breast Neoplasms; Brain Neoplasms; Polycystic Kidney, Autosomal Dominant; Brain metastases; Polycystic Kidney, Autosomal Recessive; Carcinoma, Non-Small-Cell Lung; Neoplasm Metastasis Details
WJ-13404 WJ-13404; JS-113; WJ-004 Phase 1 Clinical Wigen Biomedicine technology (Shanghai) Co Ltd Carcinoma, Non-Small-Cell Lung Details
Recombinant human anti-EGFR mAb (Serum Biotechnology) SY-101 Phase 2 Clinical Shanghai Serum Bio-Technology Co Ltd, Institute of Bioengineering Academy of Military Medical Sciences Chinese People's Liberation Army Solid tumours; Colorectal Neoplasms Details
Panitumumab-IRDye800CW (Stanford University) Phase 2 Clinical Stanford University Head and Neck Neoplasms; Brain Neoplasms Details
BAY-2927088 BAY-2927088; BAY2927088 Phase 1 Clinical Bayer Healthcare Company Ltd, Bayer AG Carcinoma, Non-Small-Cell Lung Details
Larotinib Mesylate Z-650 Phase 3 Clinical Guangdong Dongyangguang Pharmaceutical Co Ltd Solid tumours; Esophageal Neoplasms; Pancreatic Neoplasms; Esophageal Squamous Cell Carcinoma Details
Sunvozertinib DZD-9008 Phase 2 Clinical Dizal (Jiangsu) Pharmaceutical Co Ltd Lymphoma, B-Cell; Lymphoma, Non-Hodgkin; Carcinoma, Non-Small-Cell Lung Details
SKLB-1028 SKLB-1028 Phase 3 Clinical Sichuan University, CSPC Pharmaceutical Group Ltd Solid tumours; Leukemia, Promyelocytic, Acute; Leukemia, Myeloid; Leukemia, Myeloid, Acute Details
QL1203 QL-1203 Phase 3 Clinical Qilu Pharmaceutical Co Ltd Colorectal Neoplasms Details
HA121-28 HA121-28; SYHA121-28 Phase 3 Clinical CSPC Zhongqi Pharmaceutical Technology (Shijiazhuang) Co Ltd Biliary Tract Neoplasms; Solid tumours; Esophageal Neoplasms; Neoplasms; Medullary thyroid cancer (MTC); Bile Duct Neoplasms; Lung Neoplasms; Carcinoma, Non-Small-Cell Lung Details
NX-019 NX-019 Phase 1 Clinical Nalo Therapeutics Inc Neoplasms Details
TAS-2940 TAS-2940 Phase 1 Clinical Taiho Oncology Inc Solid tumours; Glioblastoma; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung Details
BL-B01D1 Phase 1 Clinical Sichuan Baili Pharmaceutical Co Ltd Neoplasms, Fibroepithelial; Solid tumours; Neoplasms; Digestive System Neoplasms; Breast Neoplasms; Urologic Neoplasms; Gastrointestinal Neoplasms Details
Zorifertinib AZD-3759 Phase 3 Clinical Astrazeneca Plc Brain metastases; Carcinoma, Non-Small-Cell Lung Details
FCN-411 FCN-411 Phase 2 Clinical Shanghai Fosun Pharmaceutical (Group) Co Ltd Lung Neoplasms; Carcinoma, Non-Small-Cell Lung Details
CX-904 CX-904 Phase 1 Clinical Amgen Inc, Cytomx Therapeutics Inc Solid tumours; Neoplasms Details
Epitinib Succinate HMPL-813 Phase 1 Clinical Solid tumours; Neoplasms; Glioblastoma; Carcinoma, Non-Small-Cell Lung Details
Pirotinib Hydrochloride KBP-5209 Phase 2 Clinical Shandong Xuanzhu Pharmaceutical Technology Co Ltd Solid tumours; Neoplasms; Breast Neoplasms; Lung Neoplasms; Carcinoma, Non-Small-Cell Lung Details
Varlitinib Ditosylate QBT-01; ARRY-543; SPS-4370; ASLAN-001; ARRY-334543 Phase 2 Clinical Array Biopharma Biliary Tract Neoplasms; Solid tumours; Stomach Neoplasms; Neoplasms; Pancreatic Neoplasms; Cholangiocarcinoma; Breast Neoplasms; Bile Duct Neoplasms Details
Antroquinonol Phase 2 Clinical Golden Biotechnology Corporation Ltd Pancreatic Neoplasms; Coronavirus Disease 2019 (COVID-19); Hepatitis B; Leukemia, Myeloid, Acute; Carcinoma, Non-Small-Cell Lung; Hyperlipidemias; Dermatitis, Atopic Details
ES-072 ES-072 Phase 1 Clinical Zhejiang Bosheng Pharmaceutical Co Ltd Carcinoma, Non-Small-Cell Lung Details
Depatuxizumab mafodotin ABT-414/806; ABT-414 Phase 3 Clinical Abbvie Inc Glioblastoma; Gliosarcoma; Glioma; Carcinoma, Squamous Cell Details
HLX-35 HLX-35 Phase 1 Clinical Shanghai Henlius Biologics Co Ltd Solid tumours; Carcinoma, Non-Small-Cell Lung Details
Serclutamab talirine ABBV-321 Phase 1 Clinical Abbvie Inc Neoplasms Details
Izalontamab SI-B001; SI-1X6.4 Phase 3 Clinical Sichuan Baili Pharmaceutical Co Ltd Head and Neck Neoplasms; Solid tumours; Stomach Neoplasms; Squamous Cell Carcinoma of Head and Neck; Neoplasms, Glandular and Epithelial; Triple Negative Breast Neoplasms; Digestive System Neoplasms; Colorectal Neoplasms; Carcinoma, Squamous Cell; Esophageal Squamous Cell Carcinoma; Carcinoma, Non-Small-Cell Lung Details
Cetuximab biosimilar (Shanghai Henlius Biotech) HLX-05; JZB-29; JZB-28 Phase 1 Clinical Shanghai Henlius Biotech Co Ltd Squamous Cell Carcinoma of Head and Neck; Colorectal Neoplasms Details
JNJ-26483327 JNJ-26483327; MTKi-327; BGB-102 Phase 2 Clinical Johnson & Johnson Solid tumours; Neoplasms; Macular Degeneration Details

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