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LAG-3

LAG-3

LAG-3 Overview

Molecule Name
Lymphocyte activation gene 3 protein
Synonyms
LAG3,CD223,FDC
Drug Development Progress
Drugs in Clinical Trials31
Approved Drugs1
Highest Development StageApproved
Target Synonym
Lymphocyte activation gene 3 protein，LAG3，Lymphocyte Activating 3，Lymphocyte-Activation Gene 3，CD223 Antigen，Protein FDC，CD223，LAG-3，FDC，sLAG-3
Background
Lymphocyte activation gene 3 protein (LAG3) is also known as CD antigen CD223 and protein FDC, which belongs to immunoglobulin (Ig) superfamily and contains 4 extracellular Ig-like domains. The LAG3 gene contains 8 exons. The sequence data, exon/intron organization, and chromosomal localization all indicate a close relationship of LAG3 to CD4. LAG3 /CD223 involved in lymphocyte activation. LAG3 /CD223 binds to HLA class-II antigens.

LAG-3 Product List

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  • N***r2022-11-08
    Biotinylated Human LAG-3 / CD223 Protein, His,Avitag™ (MALS verified)
    Ordered this reagent for a binding ELISA performed for a client. Client had questions about extending the reagent expiry and getting extra documentation provided for a GMP project. Acros customer service was great in answering all of my questions and providing documentation within just a few mins. I was provided with the COA and a memo ensuring the expiry could be extended from data that Acros had collected. I was also able to talk to other scientists on the technical side of their customer services and ensure that what I was relaying to the client was accurate. Really helped out on this project and the client was very happy! Thank you Acros!
  • 1***12019-11-07
    Human LAG-3 / CD223 Protein, His Tag, low endotoxin (MALS verified)
    I purchased Acro's protein many times for experiments. LAG3 was used mostly, and the titer after immunization can reach more than 100,000. It is a very good product.
  • 1***92019-10-11
    Human LAG-3 / CD223 Protein, Mouse IgG2a Fc Tag, low endotoxin (MALS verified)
    We purchased ACRO's Human LAG3-mFc protein, and we tested its affinity with the antibody on Biacore T200. The results showed that the affinity was within the normal range, and the protein bioactivity is very good!