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Your Position: Home > BCMA

BCMA

BCMA Molecule Information

Name：B-cell maturation protein
Target Synonym：Tumor necrosis factor receptor superfamily member 17?B-cell maturation protein?CD_antigen: CD269?BCMA?TNFRSF17?BCM
Number of Launched Drugs：0
Number of Drugs in Clinical Trials：18
Lastest Research Phase：Phase ?

BCMA Protein Product ListCompare or Buy
Cat. No. Species Product Description Structure Purity Feature
BCA-HF2H1 Human FITC-Labeled Human BCMA / TNFRSF17 Protein, His Tag
BCA-HF2H1-structure
BCA-HF2H1-sds
BCA-H5253 Human Human BCMA / TNFRSF17 Protein, Mouse IgG2a Fc Tag, low endotoxin
BCA-H5253-structure
BCA-H5253-sds
BCA-H5253-elisa_1
BCA-M52H3 Mouse Mouse BCMA / TNFRSF17 Protein, His Tag
BCA-M52H3-structure
BCA-M52H3-sds
BCA-M52H3-elisa_1
BCA-H82E4 Human Biotinylated Human BCMA / TNFRSF17 Protein, His Tag, Avi Tag (Avitag™)
BCA-H82E4-structure
BCA-H82E4-sds
BCA-H82E4-elisa_1
BCA-H5259 Human Human BCMA / TNFRSF17 Protein, Llama IgG2b Fc Tag, low endotoxin
BCA-H5259-structure
BCA-H5259-sds
BCA-H5259-elisa_1
BCA-C52H7 Cynomolgus / Rhesus macaque Cynomolgus / Rhesus macaque BCMA / TNFRSF17 Protein
BCA-C52H7-structure
BCA-C52H7-sds
BCA-C52H7-elisa_1
BCA-M82F0 Mouse Biotinylated Mouse BCMA / TNFRSF17 Protein, Fc Tag, Avi Tag (Avitag™)
BCA-M82F0-structure
BCA-M82F0-sds
BCA-M82F0-elisa_1
BCA-M5258 Mouse Mouse BCMA / TNFRSF17 Protein, Fc Tag
BCA-M5258-structure
BCA-M5258-sds
BCA-M5258-elisa_1
BCA-C5253 Cynomolgus / Rhesus macaque Cynomolgus / Rhesus macaque BCMA / TNFRSF17 Protein, Fc Tag
BCA-C5253-structure
BCA-C5253-sds
BCA-C5253-elisa_1
BCA-C82F4 Cynomolgus Biotinylated Cynomolgus / Rhesus macaque BCMA / TNFRSF17 Protein, Fc Tag, Avi Tag (Avitag™)
BCA-C82F4-structure
BCA-C82F4-sds
BCA-C82F4-elisa_1
BC7-H82F0 Human Biotinylated Human BCMA / TNFRSF17 Protein, Fc Tag, Avi Tag (Avitag™)
BC7-H82F0-structure
BC7-H82F0-sds
BC7-H82F0-elisa_1
BCA-H522y Human Human BCMA / TNFRSF17 Protein,His Tag
BCA-H522y-structure
BCA-H522y-sds
BCA-H522y-elisa_1
BCA-H522y-elisa_2
BCA-HF254 Human FITC-Labeled Human BCMA / TNFRSF17 Protein, Fc Tag
BCA-HF254-structure
BCA-HF254-sds
BCA-HF254-elisa_1
BC7-H5254 Human Human BCMA / TNFRSF17 Protein, Fc Tag
BC7-H5254-structure
BC7-H5254-sds
BC7-H5254-elisa_1

BCMA Molecule Synonym Name

TNFRSF17,CD269,BCM,BCMA

BCMA Molecule Background

Tumor necrosis factor receptor superfamily member 17 (TNFRSF17) is also known as B-cell maturation protein (BCMA), CD antigen CD269, which is a member of the TNF-receptor superfamily. TNFRSF17 contains one TNFR-Cys repeat. TNFRSF17 is expressed in mature B-cells, but not in T-cells or monocytes. TNFRSF17 is receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. TNFRSF17 promotes B-cell survival and plays a role in the regulation of humoral immunity. TNFRSF17 can activate NF-kappa-B and JNK.

BCMA References

BCMA Related Molecule

BAFF

BCMA Clinical Drug Information

Name Research Code Research Phase Company Indications Clinical Trials
BI-836909 BI-836909; AMG-420,BI836909 Phase Ⅰ Boehringer Ingelheim Multiple myeloma (MM) Details
LCAR-B38M cell product JNJ-4528; JNJ-68284528; LCAR-B38M, JNJ 4528 Phase Ⅱ Nanjing Chuanqi Biotech, Janssen Multiple myeloma (MM) Details
BCMA-CART (PD-1 knockdown, Unicar-Therapy Bio-medicine Technology) IND Filing Unicar-Therapy Bio-medicine Technology Multiple myeloma (MM) Details
GSK-2857916 GSK-2857916; J6M0-mcMMAF Phase Ⅱ GlaxoSmithKline hematological malignancies, Multiple myeloma (MM) Details
bb-2121 bb-2121 Phase Ⅱ bluebird bio, Celgene Multiple myeloma (MM) Details
CART-BCMA CART-BCMA; MTV-273,CART BCMA,MTV273 Phase Ⅰ University of Pennsylvania, Novartis Multiple myeloma (MM) Details
P-BCMA-101 P-BCMA-101,P-BCMA101 Phase Ⅰ Poseida Therapeutics Multiple myeloma (MM) Details
MEDI-2228 MEDI-2228,MEDI 2228,MEDI2228 Phase Ⅰ MedImmune Multiple myeloma (MM) Details
SEA-BCMA SEA-BCMA; SGN-BCMA Phase Ⅰ Seattle Genetics Multiple myeloma (MM) Details
bb-21217 bb-21217,bb 21217,bb21217 Phase Ⅰ bluebird bio, Celgene Multiple myeloma (MM) Details
KITE-585 KITE-585,KITE585 Phase Ⅰ Kite Pharma, National Cancer Institute Multiple myeloma (MM) Details
PF-06863135 PF-06863135,PF 06863135 Phase Ⅰ Pfizer Multiple myeloma (MM) Details
CAR-BCMA T cell therapy CT-053,CT053; CT 053 Phase Ⅰ CARsgen Multiple myeloma (MM) Details
BCMA-CART IND Filing Shanghai Hrain Biotechnology Multiple myeloma (MM) Details
AUTO-2 AUTO-2; SUB-96123,AUTO 2; SUB 96123 Phase Ⅱ Autolus Multiple myeloma (MM) Details
CC-93269 CC-93269; EM-901 Phase Ⅰ Celgene Multiple myeloma (MM) Details
ACTR 087/SEA BCMA combination therapy Phase Ⅰ Unum Therapeutics, Seattle Genetics Multiple myeloma (MM) Details
anti-BCMA CAR T-cell Therapy (Juno Therapeutics) ET-140; ET140-CAR; JCARH-125,FCARH143,MCARH171 Phase Ⅱ Juno Therapeutics Acute lymphoblastic leukaemia (ALL), Non-Hodgkin B-cell lymphomas Details

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