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PD-L1

PD-L1 Product List

Cat. No. Species Product Description Structure Purity Feature
PD1-C5253 Cynomolgus Cynomolgus / Rhesus macaque PD-L1 / B7-H1 Protein, Fc Tag
PD1-C5253-structure
PD1-C5253-sds
PD1-C5253-elisa_1
PD1-C52H4 Cynomolgus Cynomolgus / Rhesus macaque PD-L1 / B7-H1 Protein
PD1-C52H4-structure
PD1-C52H4-sds
PD1-C52H4-elisa_1
PD1-H5229 Human Human PD-L1 / B7-H1 Protein (HPLC-verified)
PD1-H5229-structure
PD1-H5229-sds
PD1-H5229-hplc
PD1-H5229-elisa_1
PD1-H9229 Human Human PD-L1 / B7-H1 Protein, C13 and N15-labeled
PD1-H9229-structure
PD1-H9229-sds
PD1-H5258 Human Human PD-L1 / B7-H1 Protein, Fc Tag, low endotoxin
PD1-H5258-structure
PD1-H5258-sds
PD1-H5258-hplc
PD1-H5258-elisa_1
PD1-H82E5 Human Biotinylated Human PD-L1 / B7-H1 (recommended for biopanning), Avi Tag (Avitag™)
PD1-H82E5-structure
PD1-H82E5-sds
PD1-H82E5-elisa_1
PD1-H5282 Human Human PD-L1 / B7-H1 Protein, Strep Tag
PD1-H5282-structure
PD1-H5282-sds
PD1-H5282-elisa_1
PD1-H82F3 Human Biotinylated Human PD-L1 / B7-H1, His Tag & Fc Tag, Avi Tag (Avitag™)
PD1-H82F3-structure
PD1-H82F3-sds
PD1-H82F3-elisa_1
PDL-H82F2 Human Biotinylated Human PD-L1 / B7-H1 Protein, Fc Tag, Avi Tag (Avitag™)
PDL-H82F2-structure
PDL-H82F2-sds
PDL-H82F2-elisa_1
PD1-H52A3 Human Human PD-L1 / B7-H1 Protein, mouse IgG1 Fc Tag, low endotoxin (HPLC-verified)
PD1-H52A3-structure
PD1-H52A3-sds
PD1-H52A3-hplc
PD1-H52A3-elisa_1
PD1-M5251 Mouse Mouse PD-L1 / B7-H1 Protein, Fc Tag
PD1-M5251-structure
PD1-M5251-sds
PD1-M5251-elisa_1
PD1-M5220 Mouse Mouse PD-L1 / B7-H1 Protein
PD1-M5220-structure
PD1-M5220-sds
PD1-M5220-elisa_1
PD1-M52A2 Mouse Mouse PD-L1 / B7-H1 Protein, mouse IgG2a Fc Tag, low endotoxin
PD1-M52A2-structure
PD1-M52A2-sds
PD1-M82F5 Mouse Biotinylated Mouse PD-L1 / B7-H1, Fc Tag, Avi Tag (Avitag™)
PD1-M82F5-structure
PD1-M82F5-sds
PD1-M82F5-elisa_1

PD-L1 Molecule Synonym Name

PD-L1,CD274,B7-H1,PDCD1L1,PDCD1LG1

PD-L1 Molecule Background

Programmed cell death 1 ligand 1 (PD-L1) is also known as cluster of differentiation (CD274) or B7 homolog 1 (B7-H1), is a member of the growing B7 family of immune molecules and is involved in the regulation of cellular and humoral immune responses. B7-H1 is a cell surface immunoglobulin superfamily with two Ig-like domains within the extracellular region and a short cytoplasmic domain. PD-L1 is highly expressed in the heart, skeletal muscle, placenta and lung and weakly expressed in the thymus, spleen, kidney and liver. PD-L1 is expressed on activated T-cells, B-cells, dendritic cells, keratinocytes and monocytes. PD-L1 is up-regulated on T- and B-cells, dendritic cells, keratinocytes and monocytes after LPS and IFNG activation and up-regulated in B-cells activated by surface Ig cross-linking. PD-L1 involve in the costimulatory signal, essential for T-cell proliferation and production of IL10 and IFNG, in an IL2-dependent and a PDCD1-independent manner.

PD-L1 References

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