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CD3E & CD3G

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CD3E & CD3G Part of Bioactivity data

CDG-C52W6-SPR
Human_FcRn_Heterodimer_Protein_SPR

Bispecific T-cell Engager (CD3 X BCMA) immobilized on CM5 Chip can bind Cynomolgus CD3E&CD3G Heterodimer Protein, His Tag&Tag Free (Cat. No. CDG-C52W6) with an affinity constant of 21.7 nM as determined in a SPR assay (Biacore T200) (Routinely tested).

CDG-H52W9-SPR
Human_FcRn_Heterodimer_Protein_SPR

Human CD3 epsilon&CD3 gamma Heterodimer Protein, Fc,His Tag&Fc,Flag Tag (Cat. No. CDG-H52W9) captured on CM5 chip via Anti-human IgG Fc antibodies surface can bind Monoclonal Anti-Human CD3 Antibody, Mouse IgG2a (Clone: OKT3), Ultra-low endotoxin (Cat. No. CDE-M120a)) with an affinity constant of 39.6 nM as determined in a SPR assay (Biacore T200) (Routinely tested).

CD3E & CD3G Molecule Synonym Name

CD3 epsilon & CD3 gamma,CD3E & CD3G

CD3E & CD3G Molecule Background

T-cell surface glycoprotein CD3 delta & CD3 gamma chain, also known as CD3D & CD3G or CD3D&CD3G respectively, are single-pass type I membrane proteins. CD3D, together with CD3- epsilon(CD3E) , CD3-gamma and CD3-zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T cell receptor-CD3 complex. T cell receptor-CD3 complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways.

CD3E & CD3G References

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