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Nectin-4

Nectin-4 Protein Product ListCompare or Buy

Cat. No. Species Product Description Structure Purity Feature
NE4-H52H3 Human Human Nectin-4 Protein, His Tag
NE4-H52H3-structure
NE4-H52H3-sds

Nectin-4 Molecule Synonym Name

NECTIN4, LNIR, PRR4, PVRL4

Nectin-4 Molecule Background

Nectin-4 (gene name PVRL4, poliovirus receptor-like 4) is a 66 kDa type I transmembrane glycoprotein belonging to the Nectin family of Ig superfamily proteins. Nectins are cell adhesion molecules that play a key role in various biological processes such as polarity, proliferation, differentiation and migration, for epithelial, endothelial, immune and neuronal cells, during development and adult life. Nectin-4 is a tumor-associated antigen in 50%, 49% and 86%o of breast, ovarian and lung carcinomas, respectively, mostly on tumors of bad prognosis. Its expression is not detected in the corresponding normal tissues.

Nectin-4 References

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