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Your Position: Home > Nectin-4

Nectin-4

Nectin-4 Protein Product ListCompare or Buy

Product> Filter Results

Cat. No.	Species	Product Description
NE4-M5257	Mouse	Mouse Nectin-4 Protein, Fc Tag
NE4-HF2H3	Human	FITC-Labeled Human Nectin-4 Protein, His Tag
NE4-H5255	Human	Human Nectin-4 Protein, Fc Tag
NE4-M52H3	Mouse	Mouse Nectin-4 Protein, His Tag
NE4-C52H4	Cynomolgus	Cynomolgus Nectin-4 Protein, His Tag
NE4-H82E7	Human	Biotinylated Human Nectin-4 Protein, His,Avitag™
NE4-H52H3	Human	Human Nectin-4 Protein, His Tag

Nectin-4 Part of Bioactivity data

NE4-H5255-BLI

Loaded Human Nectin-4, Fc Tag (Cat. No. NE4-H5255) on Protein A Biosensor, can bind Human Nectin-1, His Tag (Cat. No. PV1-H5223) with an affinity constant of 0.263 μM as determined in BLI assay (ForteBio Octet Red96e) (Routinely tested).

Protocol

NE4-H5255-BLI

Loaded Human Nectin-1, His Tag (Cat. No. PV1-H5223) on HIS1K Biosensor, can bind Human Nectin-4, Fc Tag (Cat. No. NE4-H5255) with an affinity constant of 2 μM as determined in BLI assay (ForteBio Octet Red96e) (Routinely tested).

Protocol

Nectin-4 Customer Reviews

Nectin-4 Molecule Synonym Name

NECTIN4,LNIR, PRR4, PVRL4

Nectin-4 Molecule Background

Nectin-4 (gene name PVRL4, poliovirus receptor-like 4) is a 66 kDa type I transmembrane glycoprotein belonging to the Nectin family of Ig superfamily proteins. Nectins are cell adhesion molecules that play a key role in various biological processes such as polarity, proliferation, differentiation and migration, for epithelial, endothelial, immune and neuronal cells, during development and adult life. Nectin-4 is a tumor-associated antigen in 50%, 49% and 86%o of breast, ovarian and lung carcinomas, respectively, mostly on tumors of bad prognosis. Its expression is not detected in the corresponding normal tissues.